161007-95-0Relevant articles and documents
Boronic acid-catalyzed final-stage site-selective acylation for the total syntheses of O-3′-acyl bisabolol β-D-fucopyranoside natural products and their analogues
Nakamura, Yuki,Ochiai, Takayuki,Makino, Kazuishi,Shimada, Naoyuki
, p. 281 - 285 (2021/03/08)
The first concise total syntheses of O-3′-senecioyl α-bisabolol β-D-fucopyranoside (4a) and O-3′isovaleroyl α-bisabolol β-D-fucopyranoside (4b) were achieved through final-stage site-selective acylation via the activation of cis-vicinal diols by imidazole
Synthesis and evaluation of four hederagenin glycosides as α-glucosidase inhibitor
Liu, Qing-Chao,Guo, Tian-Tian,Guo, Shou-Dong,Li, Wen-Hong,Li, Dong
, p. 142 - 149 (2013/03/14)
The four hederagenin glycosides 1-4 were efficiently synthesized through one-pot sequential glycosylations with glycose 1-(trichloroacetimidate)s as donors, resulting in a significantly simplified synthetic procedure without isolation of glycosylation intermediates. The activity of the synthetic hederagenin glycosides 1-4 against α-glucosidase type IV was evaluated; hederagenin glycoside 4 containing an α-L-rhamnopyranosyl unit showed the best activity with an IC50 value of 47.9 μM. Copyright
Synthesis and cytotoxicity evaluation of natural α-bisabolol β-d-fucopyranoside and analogues
Piochon, Marianne,Legault, Jean,Gauthier, Charles,Pichette, Andre
experimental part, p. 228 - 236 (2009/09/05)
α-Bisabolol β-d-fucopyranoside, a cytotoxic naturally occurring compound, was efficiently synthesized along with five other α-bisabolol glycosides (β-d-glucoside, β-d-galactoside, α-d-mannoside, β-d-xyloside and α-l-rhamnoside). Glycosidation of α-bisabol