16017-75-7 Usage
Description
1,7-Dimethyl-2-chloro-6-oxo-purine, also known as 8-chloro-1,3-dimethylxanthine, is a chemical compound with the molecular formula C7H7ClN4O. It is a derivative of the purine base and is commonly used as a research tool in the study of adenosine receptors.
Uses
Used in Pharmaceutical Research:
1,7-DIMETHYL-2-CHLORO-6-OXO-PURINE is used as a research tool for investigating adenosine receptors, particularly for exhibiting competitive antagonism at adenosine A1 and A2A receptors. This makes it valuable in exploring the physiological and pathological roles of adenosine in the central nervous system and other tissues.
Used in Neurological Disorder Research:
1,7-DIMETHYL-2-CHLORO-6-OXO-PURINE is used as a potential therapeutic agent for the treatment of various neurological disorders, including Parkinson's disease and chronic pain. Its study contributes to the understanding of adenosine's role in these conditions and the development of new treatment strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 16017-75-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,1 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 16017-75:
(7*1)+(6*6)+(5*0)+(4*1)+(3*7)+(2*7)+(1*5)=87
87 % 10 = 7
So 16017-75-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H7ClN4O/c1-11-3-9-5-4(11)6(13)12(2)7(8)10-5/h3H,1-2H3
16017-75-7Relevant articles and documents
2,6-Dialkoxy-7-methylpurines
Kowalska, Alicja,Maslankiewicz, Andrzej,Syrek, Barbara,Cieplinski, Piotr
, p. 341 - 352 (1985)
The preparation of unsymmetrical 2,6-dialkoxy-7-methylpurines (2), and 2-alkoxy-1,7-dialkyl-6-oxo-1,6-dihydropurines (5) is described.In contrast to 1 and 2, a facile thermal lactim-lactam rearrangement from hypoxanthines 5 and 7 into xanthines 6 was observed. - Keywords: Nucleophilic heteroaromatic substitution; thermal lactim-lactam rearrangement; Sigmatropic shifts; Dialkoxy-7H-purines; Dialkyl-1H(or 3H),7H-hypoxanthines; Trialkyl-7H-xanthines