158220-66-7

Basic information

• Product Name: (S)-4-Benzyl-3-((R)-2-methyl-hex-4-ynoyl)-oxazolidin-2-one
• Synonyms: (S)-4-Benzyl-3-((R)-2-methyl-hex-4-ynoyl)-oxazolidin-2-one
• CAS NO: 158220-66-7
• Molecular Weight: 285.343
• Mol File: 158220-66-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-Benzyl-3-((R)-2-methyl-hex-4-ynoyl)-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-Benzyl-3-((R)-2-methyl-hex-4-ynoyl)-oxazolidin-2-one(158220-66-7)
• EPA Substance Registry System: (S)-4-Benzyl-3-((R)-2-methyl-hex-4-ynoyl)-oxazolidin-2-one(158220-66-7)

Safety Data

• Hazardous Substances Data: 158220-66-7(Hazardous Substances Data)

Upstream product

• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 131685-53-5 (S)-4-benzyl-3-propionyl-2-oxazolidinone 
• 3355-28-0 1-Bromo-2-butyne 

Downstream Products

• 59865-23-5 (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-methylamino-6-octenoic acid 

Relevant articles and documents

A short synthesis of the unusual amino acid of cyclosporine (4R)-4-[(E)-2-butenyl]-4,N-dimethyl-L-threonine (MeBmt)

MeBmt 1 was prepared in four steps from the optically pure (2Z, 4R) 4-methyloct-6-yn-2-en-1-ol 8, Z allylic alcohol containing an alkynyl group at the γ position. The two stereogenic centers C-2 and C-3 in the product were controlled using Sharpless' epoxidation and subsequent ring opening at C-2 of the epoxy acid 10 with methylamine.