157542-48-8

Basic information

• Product Name: D-2,3-O-cyclohexylidene-1,4,5,6-tetra-O-(bisbenzyloxyphosphoryl)-myo-inositol
• Synonyms: D-2,3-O-cyclohexylidene-1,4,5,6-tetra-O-(bisbenzyloxyphosphoryl)-myo-inositol
• CAS NO: 157542-48-8
• Molecular Weight: 1301.2
• Mol File: 157542-48-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: D-2,3-O-cyclohexylidene-1,4,5,6-tetra-O-(bisbenzyloxyphosphoryl)-myo-inositol(CAS DataBase Reference)
• NIST Chemistry Reference: D-2,3-O-cyclohexylidene-1,4,5,6-tetra-O-(bisbenzyloxyphosphoryl)-myo-inositol(157542-48-8)
• EPA Substance Registry System: D-2,3-O-cyclohexylidene-1,4,5,6-tetra-O-(bisbenzyloxyphosphoryl)-myo-inositol(157542-48-8)

Safety Data

• Hazardous Substances Data: 157542-48-8(Hazardous Substances Data)

Upstream product

• 108549-23-1 Dibenzyl N,N-diisopropylphosphoramidite 
• 57029-87-5 (±)-1,2-cyclohexylidene myo-inositol 

Downstream Products

• 28841-60-3 D-myo-inositol 1,4,5,6-tetrakisphosphate 

Relevant articles and documents

Yb(OTf)3-Catalyzed Desymmetrization of myo-Inositol 1,3,5-Orthoformate and Its Application in the Synthesis of Chiral Inositol Phosphates

A variety of inositol phosphates including myo-inositol 1,4,5-trisphosphate, which is a secondary messenger in transmembrane signaling, were selectively synthesized via Yb(OTf)3-catalyzed desymmetrization of myo-inositol 1,3,5-orthoformate using a proline-based chiral anhydride as an acylation precursor. The investigated catalytic system could regioselectively differentiate the enantiotopic hydroxy groups of myo-inositol 1,3,5-orthoformate in the presence of a chiral auxiliary. This key step to generate a suitably protected chiral myo-inositol derivatives is described here as a unified approach to access inositol phosphates.

A convenient chemoenzymatic synthesis of D-and L-myo-inositol 1,4,5,6-tetrakisphosphate

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