155155-64-9 Usage
Description
METHYL (PHENYL 5-ACETAMIDO-4,7,8,9-TETRA-O-ACETYL-3,5-DIDEOXY-2-THIO-D-GLYCERO-D-GALACTO-2-NONULOPYRANOSID)ONATE, also known as Methyl 5-Acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-S-phenyl-2-thio-D-glycero-D-galacto-2-nonulopyranosylonate (CAS# 155155-64-9), is a complex organic compound with a unique chemical structure. It is characterized by its acetamido and acetyl functional groups, as well as its thio and nonulopyranosyl components. METHYL (PHENYL 5-ACETAMIDO-4,7,8,9-TETRA-O-ACETYL-3,5-DIDEOXY-2-THIO-D-GLYCERO-D-GALACTO-2-NONULOPYRANOSID)ONATE serves as a crucial building block in the synthesis of various complex molecules, particularly in the field of biochemistry and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
METHYL (PHENYL 5-ACETAMIDO-4,7,8,9-TETRA-O-ACETYL-3,5-DIDEOXY-2-THIO-D-GLYCERO-D-GALACTO-2-NONULOPYRANOSID)ONATE is used as a building block for the preparation of ganglioside GM3 analogs. These analogs are essential in the development of novel therapeutic agents targeting various diseases, including cancer and neurodegenerative disorders. The compound's unique structure allows for the creation of molecules with specific biological activities, making it a valuable asset in the pharmaceutical industry.
Used in Biochemical Research:
In the field of biochemistry, METHYL (PHENYL 5-ACETAMIDO-4,7,8,9-TETRA-O-ACETYL-3,5-DIDEOXY-2-THIO-D-GLYCERO-D-GALACTO-2-NONULOPYRANOSID)ONATE is employed as a key intermediate in the synthesis of complex carbohydrates and glycoconjugates. These molecules play crucial roles in cellular recognition, signal transduction, and immune responses. The compound's versatility in chemical modifications enables researchers to study the structure-function relationships of various biologically active molecules, contributing to a deeper understanding of cellular processes and the development of targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 155155-64-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,1,5 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 155155-64:
(8*1)+(7*5)+(6*5)+(5*1)+(4*5)+(3*5)+(2*6)+(1*4)=129
129 % 10 = 9
So 155155-64-9 is a valid CAS Registry Number.
InChI:InChI=1/C26H33NO12S/c1-14(28)27-22-20(36-16(3)30)12-26(25(33)34-6,40-19-10-8-7-9-11-19)39-24(22)23(38-18(5)32)21(37-17(4)31)13-35-15(2)29/h7-11,20-24H,12-13H2,1-6H3,(H,27,28)/t20-,21+,22+,23+,24+,26?/m0/s1
155155-64-9Relevant articles and documents
Synthesis of N,N-Ac,Boc laurylthio sialoside and its application to O-sialylation
Ikeda, Kiyoshi,Miyamoto, Keisuke,Sato, Masayuki
, p. 7431 - 7435 (2007)
The combination of the 5-N-tert-butoxycarbonyl (Boc) group of laurylthio sialoside and cyclopentyl methyl ether (CPME) as a solvent enhanced the reactivity and α-selectivity of the sialyl donor during sialylation. Selective deprotection of the N-Boc group
Approaches to intramolecular sialylation 2. * Synthesis of per-O-acetylated thioglycosides of N-acetylneuraminic acid containing an unprotected carboxy group
Kononov,Shpirt,Ito,Ogawa
, p. 1442 - 1446 (2007/10/03)
Various approaches to the synthesis of per-O-acetylated thioglycosides of N-acetylneuraminic acid (Neu5Ac) containing an unprotected carboxy group starting from the corresponding methyl esters were comparatively studied. One-step demethylation of methyl t