15386-52-4

Basic information

• Product Name: 1,2-Benzenediol,4-(2-amino-4-thiazolyl)-(9CI)
• Synonyms: 1,2-Benzenediol,4-(2-amino-4-thiazolyl)-(9CI);4-(2-Amino-4-thiazolyl)-1,2-benzenediol
• CAS NO: 15386-52-4
• Molecular Formula: C₉H₈N₂O₂S
• Molecular Weight: 208.23702
• Product Categories: ALCOHOL
• Mol File: 15386-52-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-Benzenediol,4-(2-amino-4-thiazolyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediol,4-(2-amino-4-thiazolyl)-(9CI)(15386-52-4)
• EPA Substance Registry System: 1,2-Benzenediol,4-(2-amino-4-thiazolyl)-(9CI)(15386-52-4)

Safety Data

• Hazardous Substances Data: 15386-52-4(Hazardous Substances Data)

Usage

Structure

A derivative of 1,2-benzenediol with a thiazole ring and an amino group at the 2-position.

Biological activity

Potential biological activity, which may be useful in pharmaceutical research or drug development.

Structural features

Thiazole ring and amino group at the 2-position contribute to the compound's potential pharmacological properties.

Further research

Additional study may be needed to fully understand the potential uses and effects of this chemical compound.

Upstream product

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• 120-80-9 benzene-1,2-diol 
• 64-17-5 ethanol 

Downstream Products

• 85849-80-5 N-[4-(3,4-Dihydroxy-phenyl)-thiazol-2-yl]-oxalamic acid 
• 26245-49-8 3-[4-(3,4-dihydroxy-phenyl)-thiazol-2-ylamino]-1-phenyl-propan-1-one 
• 26245-51-2 1-(4-bromo-phenyl)-3-[4-(3,4-dihydroxy-phenyl)-thiazol-2-ylamino]-propan-1-one 

Relevant articles and documents

An efficient strategy for protecting dihydroxyl groups of catechols

A novel strategy for protecting dihydroxyl groups of catechols has been developed. Base-mediated cyclizations of catechols with 1,3-dibromopropane provided the corresponding benzo[b]1,4-dioxepans, and herefrom the protecting group was easily cleaved by aluminum chloride. The preparation of the antibacterial and antifungal agent 4-(2-aminothiazol-4-yl)benzene-1,2-diol from catechol reliably verified its availability amenable to various harsh reaction conditions. Georg Thieme Verlag Stuttgart - New York.

Synthesis of some new 4-{2-[(aryl)amino]-1,3-thiazol-4-yl}benzene-1,2-diols as possible antibacterial and antifungal agents

Some new 4-{2-[(aryl) amino]-1,3-thiazol-4-yl}benzene-1,2-diols are prepared and characterized by spectral analysis. The newly prepared compounds are studied for their antibacterial and antifungal activity. Interestingly, almost all the compounds are found to possess promising antibacterial and antifungal activity against all tested microorganisms. Copyright Taylor & Francis Group, LLC.