152885-90-0

Basic information

• Product Name: (2R)-2-hydroxypentanoic acid benzyl ester
• Synonyms: (2R)-2-hydroxypentanoic acid benzyl ester
• CAS NO: 152885-90-0
• Molecular Weight: 208.257
• Mol File: 152885-90-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R)-2-hydroxypentanoic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-hydroxypentanoic acid benzyl ester(152885-90-0)
• EPA Substance Registry System: (2R)-2-hydroxypentanoic acid benzyl ester(152885-90-0)

Safety Data

• Hazardous Substances Data: 152885-90-0(Hazardous Substances Data)

Upstream product

• 2013-12-9 D-norvaline 
• 52709-42-9 benzylglyoxylate 
• 895583-83-2 (R)-2-hydroxypent-4-enoic acid benzyl ester 

Downstream Products

• 152830-15-4 (2R)-2-(((3-phenylpropyl)hydroxyphosphoryl)oxy)pentanoic acid benzyl ester 
• 152830-23-4 (2R)-2-(((3-phenylpropyl)hydroxyphosphoryl)oxy)penatnoic acid 
• 1026504-17-5 (R)-2-Oxo-2-(3-phenyl-propyl)-5-propyl-2λ⁵-[1,3,2]dioxaphospholan-4-one 
• 108340-61-0 (R)-1,2-pentanediol 

Relevant articles and documents

Catalytic asymmetric allylation of aldehydes using the chiral (salen)chromium(III) complexes

The enantioselective addition of allylstannanes to glyoxylates and glyoxals, as well as simple aromatic and aliphatic aldehydes, catalyzed by chiral (salen)Cr(III) complexes, has been studied. The reaction proceeded smoothly for the reactive 2-oxoaldehydes and allyltributyltin in the presence of small amounts (1-2 mol %) of (salen)Cr(III)BF4 (1b) under mild, undemanding conditions. However, in the case of other simple aldehydes, the use of high-pressure conditions is required to obtain good yields. Classic chromium catalyst 1b, easily prepared from the commercially available chloride complex 1a, affords homoallylic alcohols usually in good yield and with enantiomeric purity of 50-79% ee. The stereochemical results are rationalized on the basis of the proposed model.