15046-59-0

Basic information

• Product Name: Methanone, phenyl(6-phenyl-3-pyridazinyl)-
• CAS NO: 15046-59-0
• Molecular Formula: C17H12N2O
• Molecular Weight: 260.295
• Mol File: 15046-59-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methanone, phenyl(6-phenyl-3-pyridazinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, phenyl(6-phenyl-3-pyridazinyl)-(15046-59-0)
• EPA Substance Registry System: Methanone, phenyl(6-phenyl-3-pyridazinyl)-(15046-59-0)

Safety Data

• Hazardous Substances Data: 15046-59-0(Hazardous Substances Data)

Upstream product

• 73535-72-5 α-phenyl-α-(6-phenylpyridazin-3-yl)-acetonitrile 

Downstream Products

• 246158-90-7 α-(6-Phenylpyridazin-3-yl)benzyl chloride 
• 15045-95-1 Phenyl(6-phenylpyridazin-3-yl)methanol 

Relevant articles and documents

Synthesis, reactions and spectroscopy of 3-benzoyl-6-phenylpyridazines of expected biological activity

Oxidative decyanation of phenyl(6-phenylpyridazin-3-yl)acetonitrile (1) in methanol yielded 3-benzoyl-6-phenylpyridazine (2). Phenyl(6-phenyl-pyridazin-3-yl)methanol (3) has been obtained via NaBH4 reduction of ketone 2. Reaction of 2 with hydroxylamine or its O-alkyl analogue has been found to yield 3-benzoyloxime-6-phenylpyridazine (4) and alkyloximes (5), respectively. Treatment of 4 with a mixture of acetic acid and sulfuric acid afforded ketone 2 again and not the rearranged products (6 or 7). Beckmann rearrangement has however been achieved for 3-benzoyl(O-ethyloxime)-6-phenylpyyridazine (5a) and oxime 4 giving solely 3-carboxanilide-6-phenylpyridazine (6). 4-Benzoyloxime-3-phenyl-6-chloropyridazine (17) has been synthesized from the corresponding ketone 16.