148934-66-1 Usage
General Description
Methyl 3-chloro-1-methyl-1H-pyrazole-4-carboxylate is a chemical compound with the molecular formula C6H7ClN2O2. It is a chlorinated derivative of pyrazole and is often used as an intermediate for the synthesis of pharmaceuticals and agrochemicals. Methyl 3-chloro-1-methyl-1H-pyrazole-4-carboxylate is known for its diverse biological activities, including antimicrobial, anti-inflammatory, and antifungal properties. It is commonly used in the production of pesticides and herbicides due to its ability to inhibit the growth of certain microorganisms and pests. Additionally, it has potential applications in the development of drugs for treating various diseases and disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 148934-66-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,9,3 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 148934-66:
(8*1)+(7*4)+(6*8)+(5*9)+(4*3)+(3*4)+(2*6)+(1*6)=171
171 % 10 = 1
So 148934-66-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H7ClN2O2/c1-9-3-4(5(7)8-9)6(10)11-2/h3H,1-2H3
148934-66-1Relevant articles and documents
Synthesis of Halosulfuron-methyl via Selective Chlorination at 3- and/or 5-Position of Pyrazole-4-carboxylates
Morimoto, Katsushi,Sato, Toshiaki,Yamamoto, Susumu,Takeuchi, Hiroshi
, p. 537 - 540 (2007/10/03)
Reactions of methyl pyrazole-4-carboxylates 4b-d with N-chlorosuccinimide under heating conditions without a solvent gave methyl 3,5-dichloro-1-methylpyrazole-4-carboxylate 4a in good yields. The reaction of 4a with sodium hydrosulfide led to a nucleophilic substitution on the 5-position regioselectively to afford methyl 3-chloro-1-methyl-5-mercaptopyrazole-4-carboxylate 6a, which was followed by oxidative chlorination and amination to obtain 3-chloro-1-methyl-5-sulfamoylpyrazole-4-carboxylate 2a. Finally, the reaction of 2a with phenyl 4,6-dimethoxypyrimidin-2-yl carbamate 7 provided methyl 3-chloro-5-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-1-methylpyrazole-4- carboxylate (halosulfuron-methyl) 1a promising herbicide in corn.
