148356-36-9Relevant articles and documents
Synthesis of Talosin A and B, two bioactive isoflavonoid glycosides
Wu, Zhongtao,Lian, Gaoyana,Yu, Biao,Wang, Zhenzhongc,Zhao, Yiwuc,Xiao, Wei
experimental part, p. 1725 - 1730 (2011/07/07)
Talosin A and B, namely genistein 7-O-α-L-6-deoxy-talopyranoside and genistein 4',7-di-O-α-L-6-deoxytalopyranoside, which show excellent antifungal and anti-inflammatory activities, were synthesized concisely.
Syntheses of Isoflavones and Isoflavone Glycosides, and Their Inhibitory Activity against Bovine Liver &β-Galactosidase
Nishiyama, Kiyotoshi,Esaki, Sachiko,Deguchi, Ikuko,Sugiyama, Naoko,Kamiya, Shintaro
, p. 107 - 114 (2007/10/02)
To clarify the relationship between the structure and inhibitory action toward β-D-galactosidase (EC 3.2.1.21) of isoflavones and isoflavone glycosides, a number of polyhydroxyisoflavones, and the α-L-rhamnosides and β-L-quinovosides of daidzein and genistein were synthesized.Among the polyhydroxyisoflavones, 2',3',4',7-tetrahydroxyisoflavone showed the strongest inhibitory activity (Ki = 26 * 10-6 M).Among the glycosides, all the L-rhamnosides were strong inhibitors, of which genistein 4',7-di-O-α-L-rhamnoside was the strongest (Ki = 4.44 * 10-6 M), while all the isoflavone β-L-quinovosides were considerably weak or possessed no inhibition.