147611-81-2

Basic information

• Product Name: DBD-NCS
• Synonyms: DBD-NCS [=4-(N,N-Dimethylaminosulfonyl)-7-isothiocyanato-2,1,3-benzoxadiazole] [for HPLC Labeling and Edman Degradation];DBD-NCS [=4-(N,N-Dimethylaminosulfonyl)-7-isothiocyanato-2,1,3-benzoxadiazole];DBD-NCS [=4-(N,N-Dimethylaminosulfonyl)-7-isothiocya;4-(N,N-Dimethylaminosulfonyl)-7-isothiocyanatobenzofurazan 4-(N,N-Dimethylaminosulfonyl)-7-isothiocyanato-2,1,3-benzoxadiazole;[=4-(N,N-DiMethylaMinosulfonyl)-7-isothiocyanato-2,1,3-benzoxadiazole] [for HPLC Labeling and EdMan Degradation];DBD-NCS 4-(N,N-DIMETHYLAMINOSULFONYL)-7-ISOTHIOCYANATO-2,1,3-BENZOXADIAZOLE;4-(N,N-DIMETHYLAMINOSULFONYL)-7-ISOTHIOCYANATOBENZOFURAZAN
• CAS NO: 147611-81-2
• Molecular Formula: C9H8N4O3S2
• Molecular Weight: 284.31
• Product Categories: Amino Group Labeling Reagents for Fluorescence HPLC;Analytical Chemistry;Fluorescence Detection (HPLC Labeling Reagents);HPLC Labeling Reagents
• Mol File: 147611-81-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 126°C
• Boiling Point: 458.1°Cat760mmHg
• Flash Point: 230.8°C
• Appearance: /
• Density: 1.58g/cm³
• Vapor Pressure: 1.42E-08mmHg at 25°C
• Refractive Index: 1.711
• Storage Temp.: Refrigerator
• PKA: -4.33±0.50(Predicted)
• CAS DataBase Reference: DBD-NCS(CAS DataBase Reference)
• NIST Chemistry Reference: DBD-NCS(147611-81-2)
• EPA Substance Registry System: DBD-NCS(147611-81-2)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 147611-81-2(Hazardous Substances Data)

Usage

General Description

DBD-NCS (N,N-Diisopropylethylamine-NCS) is a chemical compound that is commonly used as a reagent in organic synthesis. It is an isothiocyanate derivative of an amine and is often used as a nucleophilic reagent in the modification of proteins and peptides for chemical and biological studies. It reacts with amino groups of proteins to form stable thiourea derivatives, which are commonly used for protein labeling and modification. DBD-NCS is also used in the preparation of amine-reactive fluorescent dyes and in the synthesis of peptide coupling reagents. Due to its stability and reactivity, DBD-NCS is a valuable tool in chemical biology and bioconjugation chemistry.

InChI:InChI=1/C9H8N4O3S2/c1-13(2)18(14,15)7-4-3-6(10-5-17)8-9(7)12-16-11-8/h3-4H,1-2H3