146982-24-3 Usage
Description
Fmoc-Asp(OAll)-OH, also known as N-(9-fluorenylmethoxycarbonyl)-L-aspartic acid α-allyl ester, is a synthetic amino acid derivative used as a building block in the synthesis of peptides. It is a white crystalline powder with specific chemical properties that make it suitable for peptide synthesis.
Uses
Used in Pharmaceutical Industry:
Fmoc-Asp(OAll)-OH is used as a building block for peptide synthesis, which is crucial for the development of new pharmaceuticals and therapeutics. The growing peptide drug market demands fast and reliable synthesis methods, making Fmoc-Asp(OAll)-OH an essential component in the pharmaceutical industry.
Used in Research and Development:
In the field of research and development, Fmoc-Asp(OAll)-OH is used as a key component in the synthesis of various peptide sequences. This allows scientists to study the structure, function, and potential applications of these peptides in different biological systems.
Used in Drug Delivery Systems:
Fmoc-Asp(OAll)-OH can also be utilized in the development of drug delivery systems, where it can be incorporated into peptide-based drug carriers. These carriers can improve the targeting, bioavailability, and overall efficacy of therapeutic agents.
Used in Diagnostics:
In the diagnostics industry, Fmoc-Asp(OAll)-OH can be employed in the synthesis of peptide-based biomarkers or diagnostic agents. These agents can help in the early detection and monitoring of various diseases and conditions.
Overall, Fmoc-Asp(OAll)-OH plays a significant role in various applications across different industries, primarily due to its utility as a building block in peptide synthesis. Its chemical properties and versatility make it a valuable asset in the development of new pharmaceuticals, drug delivery systems, and diagnostic tools.
Check Digit Verification of cas no
The CAS Registry Mumber 146982-24-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,9,8 and 2 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 146982-24:
(8*1)+(7*4)+(6*6)+(5*9)+(4*8)+(3*2)+(2*2)+(1*4)=163
163 % 10 = 3
So 146982-24-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H21NO6/c1-2-11-28-20(24)12-19(21(25)26)23-22(27)29-13-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h2-10,18-19H,1,11-13H2,(H,23,27)(H,25,26)/t19-/m0/s1
146982-24-3Relevant articles and documents
A versatile and selective chemo-enzymatic synthesis of β-protected aspartic and γ-protected glutamic acid derivatives
Nuijens, Timo,Kruijtzer, John A.W.,Cusan, Claudia,Rijkers, Dirk T.S.,Liskamp, Rob M.J.,Quaedflieg, Peter J.L.M.
experimental part, p. 2719 - 2721 (2009/09/06)
Two versatile, high yielding, and efficient chemo-enzymatic methods for the synthesis of β-protected Asp and γ-protected Glu derivatives using Alcalase are described. The first method is based on the α-selective enzymatic hydrolysis of symmetrical aspartyl and glutamyl diesters. The second method involving mixed diesters comprises a three-step protocol using (i) α-selective enzymatic methyl-esterification, (ii) chemical β-esterification, and finally (iii) α-selective enzymatic methyl ester hydrolysis. The yields of the purified β- and γ-esters range from 77% to 91%.
