1467-21-6

Basic information

• Product Name: 1-benzyl-3-phenylurea
• Synonyms: 1-Benzyl-3-phenylurea; N-benzyl-N'-phenylurea; urea, N-phenyl-N'-(phenylmethyl)-
• CAS NO: 1467-21-6
• Molecular Formula: C₁₄H₁₄N₂O
• Molecular Weight: 226.2738
• Mol File: 1467-21-6.mol
• Article Data: 91

Chemical Properties

• Boiling Point: 366.5°C at 760 mmHg
• Flash Point: 142.2°C
• Density: 1.178g/cm³
• Vapor Pressure: 1.46E-05mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: 1-benzyl-3-phenylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3-phenylurea(1467-21-6)
• EPA Substance Registry System: 1-benzyl-3-phenylurea(1467-21-6)

Safety Data

• Hazardous Substances Data: 1467-21-6(Hazardous Substances Data)

Usage

Description

1-benzyl-3-phenylurea, a urea derivative with the molecular formula C15H14N2O, is a chemical compound that exhibits a wide range of applications in agriculture, pharmaceuticals, and organic chemistry. It is known for its ability to act as a plant growth regulator, promoting lateral branching and flowering in various crops, and enhancing fruit set, yield, quality, and shelf life.

Uses

Used in Agriculture:
1-benzyl-3-phenylurea is used as a plant growth regulator for promoting lateral branching and flowering in crops such as grapes, kiwifruit, and tomatoes. It is used to improve fruit set and yield, as well as to enhance the quality and shelf life of fruits by increasing their sugar content and reducing physiological disorders.
Used in Pharmaceutical Industry:
1-benzyl-3-phenylurea is used as a potential therapeutic agent in the pharmaceutical industry. Its exact application and mechanism of action in this field are not specified in the provided materials.
Used in Organic Chemistry:
1-benzyl-3-phenylurea is used as a reagent in various synthetic transformations in organic chemistry. Its specific applications and reactions in this field are not detailed in the provided materials.
Caution:
While 1-benzyl-3-phenylurea offers numerous benefits, it is essential to exercise caution when handling this chemical compound. It may pose health and environmental hazards if not used properly. Proper safety measures and guidelines should be followed to minimize any potential risks associated with its use.

Upstream product

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Downstream Products

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• 1371268-52-8 N-(4-iodophenyl)-N’-benzylurea 
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• 176370-52-8 6-amino-3-benzyl-1-phenylpyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

Curtius-like Rearrangement of an Iron-Nitrenoid Complex and Application in Biomimetic Synthesis of Bisindolylmethanes

A Curtius-like rearrangement of hydroxamates to isocyanates was discovered. This reaction was initiated from an iron(II)-nitrenoid complex, which was generated by the iron(II)-catalyzed cleavage of N-O bonds of functionalized hydroxamates. To demonstrate the efficiency of this new Curtius-like rearrangement in synthetic chemistry, a biomimetic strategy for the one-pot preparation of bisindolylmethanes was developed.

2,2,2-Trifluroenthanol promoted synthesis of unsymmetrical ureas from dioxazolones and amines via tandem lossen rearrangement/condensation process

A 2,2,2-trifluroenthanol (TFE) promoted synthesis of unsymmetric ureas was described. This approach enabled the construction of a variety of ureas from the readily prepared and easy-to-handle dioxazolones and amines via tandem Lossen rearrangement/condensation process. The reaction featured mild conditions for the urea synthesis under metal-free conditions, which was successively applied in the scale-up synthesis of herbicides Monuro and Isoproturon.

Stabilization of the hindered urea bond through de-tert-butylation

We report the discovery of an acid-assisted de-tert-butylation reaction that can instantly “turn off” the dynamicity of hindered urea bonds (HUBs) and thus broaden their applications. The reaction is demonstrated to be widely applicable to different hindered urea substrates, leading to improved chemical stabilities and mechanical properties of HUB-containing materials.