145372-41-4

Basic information

• Product Name: 1α-<(tert-butyldimethylsilyl)-oxy>-6,7-didehydro-24-(methoxycarbonyl)-25,26,27-trisnorprevitamin D₃ tert-butyldimethylsilyl ether
• Synonyms: 1α-<(tert-butyldimethylsilyl)-oxy>-6,7-didehydro-24-(methoxycarbonyl)-25,26,27-trisnorprevitamin D₃ tert-butyldimethylsilyl ether
• CAS NO: 145372-41-4
• Molecular Weight: 643.111
• Mol File: 145372-41-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1α-<(tert-butyldimethylsilyl)-oxy>-6,7-didehydro-24-(methoxycarbonyl)-25,26,27-trisnorprevitamin D₃ tert-butyldimethylsilyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 1α-<(tert-butyldimethylsilyl)-oxy>-6,7-didehydro-24-(methoxycarbonyl)-25,26,27-trisnorprevitamin D₃ tert-butyldimethylsilyl ether(145372-41-4)
• EPA Substance Registry System: 1α-<(tert-butyldimethylsilyl)-oxy>-6,7-didehydro-24-(methoxycarbonyl)-25,26,27-trisnorprevitamin D₃ tert-butyldimethylsilyl ether(145372-41-4)

Safety Data

• Hazardous Substances Data: 145372-41-4(Hazardous Substances Data)

Upstream product

• 145372-33-4 des-A,B-22-iodo-23,24-dinorchol-8-enyl trifluoromethanesulfonate 
• 145372-32-3 des-A,B-22-iodo-23,24-dinorcholan-8-one 
• 116535-65-0 (1R,3aR,4S,7aR)-octahydro-1-[(S)-1-iodopropan-2-yl]-7a-methyl-1H-inden-4-ol 
• 64190-52-9 (8S,20S)-de-A,B-20-(hydroxymethyl)pregnan-8-ol 
• 116506-67-3 TB 
• 145372-34-5 methyl-des-A,B-8-<(trifluoromethanesulfonyl)oxy>chol-8-ene-24-carboxylate 

Downstream Products

• 145372-43-6 1α-[(tert-butyldimethylsilyl)oxy]-24-(methoxycarbonyl)-25,26,27-trisnorvitamin D3 tert-butyldimethylsilyl ether 
• 140710-96-9 (1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-secocholesta-5(Z),7(E),10(19)-trien-25-ol 
• 32222-06-3 calcitriol 

Relevant articles and documents

Ultrasonically Induced Conjugate Addition of Iodides to Electron-Deficient Olefins and Its Application to the Synthesis of Side-Chain Analogs of the Hormone 1α,25-Dihydroxyvitamin D3

A versatile method for the rapid construction of fragments related to the upper part of vitamin D3 from the Lythgoe-Inhoffen diol is described.The key feature of the strategy is a new zinc-copper-induced conjugate addition of iodo triflate 10a to electron-deficient olefins under sonochemical aqueous conditions.These fragments are rapidly and efficiently transformed via the dienyne convergent approach to several derivatives of the hormone 1α,25-(OH)2-D3 modified at C-25.