145198-89-6

Basic information

• Product Name: N-(p-Nitrophenyl)-5-vinyl-6-aza-2-oxacyclohexan-1-one
• CAS NO: 145198-89-6
• Molecular Weight: 248.238
• Mol File: 145198-89-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(p-Nitrophenyl)-5-vinyl-6-aza-2-oxacyclohexan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: N-(p-Nitrophenyl)-5-vinyl-6-aza-2-oxacyclohexan-1-one(145198-89-6)
• EPA Substance Registry System: N-(p-Nitrophenyl)-5-vinyl-6-aza-2-oxacyclohexan-1-one(145198-89-6)

Safety Data

• Hazardous Substances Data: 145198-89-6(Hazardous Substances Data)

Upstream product

• 100-28-7 4-Nitrophenyl isocyanate 
• 113495-34-4 3-vinyl-2,6-dioxacyclohexan-1-one 

Relevant articles and documents

Regio- and stereoselective synthesis of 1,3-hydroxyl amines via palladium-catalyzed carbonate-carbamate transformation with unique stereoselectivity: Synthesis of 3-amino-4-penten-1-ols

The transformation of cyclic carbonates 1 to cyclic carbamates 4 is achieved in the presence of aryl or sulfonyl isocyanate by the catalysis of Pd(0) in high yield and with high structural flexibility. The reaction shows unique stereoselectivity: 3,4-disubstituted carbonates 2, irrespective of the composition of their stereoisomers, provide trans-5 exclusively or predominantly over cis-5. Mixtures of cis- and trans-3,5-disubstituted carbonates 3 furnish either cis-6 or trans-6 in high selectivity depending on the reaction conditions (kinetic or thermodynamic control, respectively). 1H NMR and X-ray structure analyses of 5 and 6 indicate that the stereochemical outcome is governed by an A1,2-strain between N-sulfonyl and C5-vinyl substituents.