144851-61-6

Basic information

• Product Name: 2-Amino-3-fluorobenzotrifluoride
• Synonyms: ALPHA,ALPHA,ALPHA,6-TETRAFLUORO-O-TOLUIDINE;2-FLUORO-6-(TRIFLUOROMETHYL)ANILINE;2-AMINO-3-FLUOROBENZOTRIFLUORIDE;2-Amino-3-fluorobenzotrifluoride 98%;2-Amino-3-fluorobenzotrifluoride98%;2-Amino-3-fluorobenzotrifluoride, α,α,α,6-Tetrafluoro-o-toluidine;(2-Fluoro-6-trifluoroMethylphenyl)aMine;2-Fluoro-6-(trifluoromethyl)aniline, alpha,alpha,alpha,6-Tetrafluoro-o-toluidine
• CAS NO: 144851-61-6
• Molecular Formula: C7H5F4N
• Molecular Weight: 179.11
• EINECS: 1533716-785-6
• Mol File: 144851-61-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 155 °C(lit.)
• Flash Point: 128 °F
• Appearance: Light yellow liquid
• Density: 1.388 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.6mmHg at 25°C
• Refractive Index: n20/D 1.462(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 0.07±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-3-fluorobenzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3-fluorobenzotrifluoride(144851-61-6)
• EPA Substance Registry System: 2-Amino-3-fluorobenzotrifluoride(144851-61-6)

Safety Data

• Hazard Codes: Xn,F,Xi
• Statements: 10-20/21/22-36/37/38
• Safety Statements: 16-26-27-36/37/39
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 144851-61-6(Hazardous Substances Data)

Usage

Description

2-Amino-3-fluorobenzotrifluoride is a fluorinated aromatic compound characterized by the presence of an amino group and a trifluoromethyl group. It is a valuable building block in the synthesis of various organic molecules, particularly those with potential applications in pharmaceuticals, agrochemicals, and materials science.

Uses

Used in Pharmaceutical Industry:
2-Amino-3-fluorobenzotrifluoride is used as a synthetic intermediate for the development of new pharmaceutical compounds. Its unique structure allows for the creation of molecules with specific biological activities, potentially leading to the discovery of novel drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Amino-3-fluorobenzotrifluoride is used as a key component in the synthesis of new pesticides and herbicides. Its fluorinated nature may contribute to enhanced biological activity and selectivity, making it a valuable asset in the development of more effective and environmentally friendly agrochemicals.
Used in Materials Science:
2-Amino-3-fluorobenzotrifluoride is also utilized in the field of materials science, where it can be employed in the design and synthesis of advanced materials with specific properties. These materials may find applications in various industries, such as electronics, coatings, and adhesives, due to their unique combination of chemical and physical characteristics.
Used in the Preparation of Specific Compounds:
2-Amino-3-fluorobenzotrifluoride is used as a starting material for the preparation of bis[4-amino-3-fluoro-5-(trifluoromethyl)phenyl]methane, which is an important compound in the development of new materials and pharmaceuticals. Its fluorinated nature and reactivity make it a versatile building block for the synthesis of complex molecular structures.

InChI:InChI=1/C7H5F4N/c8-5-3-1-2-4(6(5)12)7(9,10)11/h1-3H,12H2