1448-98-2 Usage
Description
N-(2-Cyanoacetyl)urea, also known as Cyanoacetylurea, is an organic compound that serves as an intermediate in the synthesis of various biologically active molecules. It is characterized by its white to off-white crystalline appearance and is derived from low-cost materials, making it a cost-effective choice for chemical synthesis.
Uses
Used in Pharmaceutical Industry:
N-(2-Cyanoacetyl)urea is used as an intermediate for the synthesis of Uridine (U829910), a nucleoside that is one of the four basic components of ribonucleic acid (RNA). This makes it a crucial component in the development of drugs targeting RNA-related diseases and conditions.
Used in Chemical Synthesis:
N-(2-Cyanoacetyl)urea is used as a starting material for the synthesis of a variety of heterocycles, which are easily prepared from low-cost materials. Its versatility in chemical reactions allows for the creation of diverse compounds, including uracils fused with different heterocyclic rings.
Used in Caffeine and SDM Production:
N-(2-Cyanoacetyl)urea is also utilized in the synthesis of caffeine and SDM (S-adenosyl-L-methionine), both of which have significant applications in the pharmaceutical and food industries. Caffeine is a widely consumed stimulant, while SDM is involved in various biological processes, including the synthesis of neurotransmitters and the methylation of DNA, RNA, and proteins.
Check Digit Verification of cas no
The CAS Registry Mumber 1448-98-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,4 and 8 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1448-98:
(6*1)+(5*4)+(4*4)+(3*8)+(2*9)+(1*8)=92
92 % 10 = 2
So 1448-98-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H5N3O2/c5-2-1-3(8)7-4(6)9/h1H2,(H3,6,7,8,9)
1448-98-2Relevant articles and documents
IMPROVEMENTS IN SYNTHESIS OF CYANOACETYLUREA (EXCHANGE OF INFORMATION)
Kolganova, D. N.,Khoroshikh, A. P.,Kryukova, Yu. I.,Sokolov, Yu. A.
, p. 285 - 286 (1983)
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IMPROVED CYANOACETYLUREA SYNTHESIS
Nesterov, V. M.,Kucherya, L. A.,Drevina, V. M.
, p. 460 - 461 (1980)
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Inhibitors of the advanced glycosylation of proteins and methods of use therefor
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, (2008/06/13)
The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylatin. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.
