14370-23-1 Usage
Description
2-ISOTHIOCYANATO-BICYCLO[2.2.1]HEPTANE, also known as exo-2-Norbornylisothiocyanate, is a chemical compound derived from the isomerization of exo-2-norbornylthiocyanate. This process involves the formation of a non-classical ion, which contributes to its unique chemical properties and potential applications in various industries.
Uses
Used in Chemical Synthesis:
2-ISOTHIOCYANATO-BICYCLO[2.2.1]HEPTANE is used as a key intermediate in the synthesis of various organic compounds, particularly those with pharmaceutical or agrochemical applications. Its unique chemical structure allows for versatile reactions and the formation of a wide range of products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-ISOTHIOCYANATO-BICYCLO[2.2.1]HEPTANE is used as a building block for the development of new drugs. Its reactivity and structural diversity make it a valuable component in the design and synthesis of novel therapeutic agents.
Used in Agrochemical Industry:
2-ISOTHIOCYANATO-BICYCLO[2.2.1]HEPTANE is also utilized in the agrochemical industry for the creation of new pesticides and other crop protection agents. Its unique properties enable the development of more effective and targeted products for agricultural use.
Used in Research and Development:
Due to its unique chemical properties and potential for isomerization, 2-ISOTHIOCYANATO-BICYCLO[2.2.1]HEPTANE is an important compound in research and development efforts. It serves as a model system for studying reaction mechanisms and exploring new synthetic pathways in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 14370-23-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,7 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 14370-23:
(7*1)+(6*4)+(5*3)+(4*7)+(3*0)+(2*2)+(1*3)=81
81 % 10 = 1
So 14370-23-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NS/c10-5-9-8-4-6-1-2-7(8)3-6/h6-8H,1-4H2/t6-,7+,8+/m1/s1
14370-23-1Relevant articles and documents
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Spurlock,L.A.,Parks,T.E.
, p. 1279 - 1284 (1970)
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Comparison of large-scale routes to manufacture chiral exo-2-norbornyl thiourea
Caille, Seb,Boni, Jerome,Cox, Geoffrey B.,Faul, Margaret M.,Franco, Pilar,Khattabi, Saab,Klingensmith, Liane M.,Larrow, Jay F.,Lee, James K.,Martinelli, Michael J.,Miller, Larry M.,Moniz, George A.,Sakai, Kenichi,Tedrow, Jason S.,Hansen, Karl B.
scheme or table, p. 133 - 141 (2010/04/29)
Two routes aimed at the manufacture of chiral exo-2-norbornyl thiourea (1) on large scale are described. The first approach involves five chemical steps and hinges on a classical resolution via diastereomeric salt formation. The synthesis utilizes amine 2 as the resolution handle. The second approach includes two chemical steps and a chiral chromatography of (±)-1. Despite the larger initial investment necessary to acquire the chiral stationary phase used in the chromatographic approach, the shorter reaction sequence and efficiency of the chromatographic separation make the second route a more attractive option for long-term applications.
