143234-87-1

Basic information

• Product Name: p-Fluorobenzonitrile
• Synonyms: p-Fluorobenzonitrileradical ion(1+)
• CAS NO: 143234-87-1
• Molecular Formula: C7H4FN
• Molecular Weight: 121.1118
• EINECS: 214-784-9
• Mol File: 143234-87-1.mol
• Article Data: 290

Chemical Properties

• Boiling Point: 189.6 °C at 760 mmHg
• Flash Point: 65.6 °C
• Appearance: /
• Density: 1.15 g/cm³
• CAS DataBase Reference: p-Fluorobenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: p-Fluorobenzonitrile(143234-87-1)
• EPA Substance Registry System: p-Fluorobenzonitrile(143234-87-1)

Safety Data

• Hazardous Substances Data: 143234-87-1(Hazardous Substances Data)

Usage

General Description

p-Fluorobenzonitrile is a chemical compound with the molecular formula C7H4F2N. It is a white crystalline solid with a strong signal in the infrared spectrum. This chemical is commonly used in organic synthesis, especially in the production of pharmaceuticals and agrochemicals. It is also used as an intermediate in the manufacturing of dyes and pigments. p-Fluorobenzonitrile is considered to be hazardous if ingested, inhaled, or comes into contact with skin. It is important to handle and store this chemical with caution, following all safety guidelines and regulations.

Upstream product

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• 67-56-1 methanol 

Downstream Products

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Relevant articles and documents

Nitrile Synthesis via Desulfonylative-Smiles Rearrangement

Herein, we designed a simple nitrile synthesis from N-[(2-nitrophenyl)sulfonyl]benzamides via base-promoted intramolecular nucleophilic aromatic substitution. The process features redox-neutral conditions as well as no requirement of toxic cyanide species and transition metals. Our process shows broad scope and various functional group compatibility, affording a variety of (hetero)aromatic nitriles in good to excellent yields.

Synthesis and Characterization of Bidentate (P^N)Gold(III) Fluoride Complexes: Reactivity Platforms for Reductive Elimination Studies

A new family of cationic, bidentate (P^N)gold(III) fluoride complexes has been prepared and a detailed characterization of the gold-fluoride bond has been carried out. Our results correlate with the observed reactivity of the fluoro ligand, which undergoes facile exchange with both cyano and acetylene nucleophiles. The resulting (P^N)arylgold(III)C(sp) complexes have enabled the first study of reductive elimination on (P^N)gold(III) systems, which demonstrated that C(sp2)?C(sp) bond formation occurs at higher rates than those reported for analogous phosphine-based monodentate systems.

Biomass chitosan-derived nitrogen-doped carbon modified with iron oxide for the catalytic ammoxidation of aromatic aldehydes to aromatic nitriles

Nitrogen-doped carbon catalysts have attracted increasing research attention due to several advantages for catalytic application. Herein, cost-effective, renewable biomass chitosan was used to prepare a N-doped carbon modified with iron oxide catalyst (Fe2O3@NC) for nitrile synthesis. The iron oxide nanoparticles were uniformly wrapped in the N-doped carbon matrix to prevent their aggregation and leaching. Fe2O3@NC-800, which was subjected to carbonization at 800 °C, exhibited excellent activity, selectivity, and stability in the catalytic ammoxidation of aromatic aldehydes to aromatic nitriles. This study may provide a new method for the fabrication of an efficient and cost-effective catalyst system for synthesizing nitriles.