1429924-47-9

Basic information

• Product Name: 4,6-dichloro-5-{(E)-[(2-chlorophenyl)hydrazono]methyl}pyrimidine
• Synonyms: 4,6-dichloro-5-{(E)-[(2-chlorophenyl)hydrazono]methyl}pyrimidine
• CAS NO: 1429924-47-9
• Molecular Weight: 301.562
• Mol File: 1429924-47-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,6-dichloro-5-{(E)-[(2-chlorophenyl)hydrazono]methyl}pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-dichloro-5-{(E)-[(2-chlorophenyl)hydrazono]methyl}pyrimidine(1429924-47-9)
• EPA Substance Registry System: 4,6-dichloro-5-{(E)-[(2-chlorophenyl)hydrazono]methyl}pyrimidine(1429924-47-9)

Safety Data

• Hazardous Substances Data: 1429924-47-9(Hazardous Substances Data)

Upstream product

• 41052-75-9 o-chlorophenylhydrazine hydrochloride 
• 5305-40-8 2,6-dichloro-pyrimidine carbaldehyde 

Downstream Products

• 852313-98-5 4-chloro-1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine 

Relevant articles and documents

Selective synthesis of 1-substituted 4-chloropyrazolo[3,4-d]pyrimidines

Strategies for carrying out the reaction of 4,6-dichloropyrimidine-5- carboxaldehyde with various hydrazines to generate 1-substituted 4-chloropyrazolo[3,4-d]pyrimidines in a selective and high-yielding manner are presented. For aromatic hydrazines, the reaction is performed in the absence of an external base, which promotes exclusive hydrazone formation. The hydrazones subsequently cyclize at an elevated temperature to form the desired pyrazolo[3,4-d]pyrimidine products. For aliphatic hydrazines, the reaction sequence proceeds as a single step in the presence of an external base.