1412975-41-7

Basic information

• Product Name: (1aR,7bS)-5-[2-((S)-1-ethylpyrrolidin-3-yloxymethyl)-4-fluorobenzene-sulfonylamino]-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid
• CAS NO: 1412975-41-7
• Molecular Weight: 490.553
• Mol File: 1412975-41-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1aR,7bS)-5-[2-((S)-1-ethylpyrrolidin-3-yloxymethyl)-4-fluorobenzene-sulfonylamino]-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1aR,7bS)-5-[2-((S)-1-ethylpyrrolidin-3-yloxymethyl)-4-fluorobenzene-sulfonylamino]-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid(1412975-41-7)
• EPA Substance Registry System: (1aR,7bS)-5-[2-((S)-1-ethylpyrrolidin-3-yloxymethyl)-4-fluorobenzene-sulfonylamino]-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid(1412975-41-7)

Safety Data

• Hazardous Substances Data: 1412975-41-7(Hazardous Substances Data)

Upstream product

• 112399-50-5 2-bromo-5-fluorobenzyl bromide 
• 101469-92-5 (S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 929543-58-8 tert-butyl (S)-3-(2-bromo-5-fluorobenzyloxy)pyrrolidine-1-carboxylate 
• 1412979-24-8 tert-butyl (S)-3-[(1aR,7bS)-5-fluoro-2-(4-methoxycarbonyl-1,1a,2,7b-tetrahydro-cyclopropa[c]chromen-5-ylsulfamoyl)benzyloxy]pyrrolidine-1-carboxylate 
• 1412979-26-0 tert-butyl (S)-3-(2-chlorosulfonyl-5-fluorobenzyloxy)pyrrolidine-1-carboxylate 
• 64241-01-6 methyl 2-amino-6-hydroxybenzoate 
• 1356113-52-4 methyl 2-(2,2-dimethylpropionylamino)-6-hydroxybenzoate 
• 1412976-28-3 methyl 2-(2,2-dimethylpropionylamino)-6-(prop-2-ynyloxy)benzoate 
• 1412976-26-1 methyl 7-(2,2-dimethylpropionylamino)-2H-chromene-8-carboxylate 
• 1412976-22-7 methyl (1aR,7bS)-5-amino-1,1 a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylate 

Relevant articles and documents

METHODS OF TREATING LIVER DISEASES

The invention provides tricyclic compounds and their use in treating liver disorders, such as non-alcoholic steatohepatitis and related disorders (e.g., fibrosis). The compounds are contemplated to have activity against methionyl aminopeptidase 2.