139719-91-8Relevant articles and documents
Synthesis of substituted azulenes via Pt(II)-Catalyzed ring-expanding cycloisomerization
Usui, Kazuteru,Tanoue, Kensuke,Yamamoto, Kosuke,Shimizu, Takashi,Suemune, Hiroshi
, p. 4662 - 4665 (2014)
Substituted azulenes, valuable structures for electronic devices and pharmaceuticals, have been synthesized by the platinum(II)-catalyzed intramolecular ring-expanding cycloisomerization of 1-en-3-yne with ortho-disubstituted benzene. This novel method provides an alternative route for the efficient synthesis of substituted azulenes. The reaction mechanism of selected catalytic transformations was explored using density functional calculations.
Novel 3-aminochromans as potential pharmacological tools for the serotonin 5-HT7 receptor
Holmberg, Paer,Tedenborg, Lars,Rosqvist, Susanne,Johansson, Anette M.
, p. 747 - 750 (2007/10/03)
The synthesis of novel C6-aryl substituted derivatives of 3-(dimethylamino)chroman is described. The novel derivatives display 5-HT 7 receptor affinities that varies from nM to μM, indicating that this small set of derivatives constitute a nove