139426-88-3

Basic information

• Product Name: <4S,3(2S,3R)>-4-benzyl-3-(3-hydroxy-2-methyl-4-pentenoyl)-2-oxazolidinone
• Synonyms: <4S,3(2S,3R)>-4-benzyl-3-(3-hydroxy-2-methyl-4-pentenoyl)-2-oxazolidinone
• CAS NO: 139426-88-3
• Molecular Weight: 289.331
• Mol File: 139426-88-3.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: <4S,3(2S,3R)>-4-benzyl-3-(3-hydroxy-2-methyl-4-pentenoyl)-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: <4S,3(2S,3R)>-4-benzyl-3-(3-hydroxy-2-methyl-4-pentenoyl)-2-oxazolidinone(139426-88-3)
• EPA Substance Registry System: <4S,3(2S,3R)>-4-benzyl-3-(3-hydroxy-2-methyl-4-pentenoyl)-2-oxazolidinone(139426-88-3)

Safety Data

• Hazardous Substances Data: 139426-88-3(Hazardous Substances Data)

Upstream product

• 131685-53-5 (S)-4-benzyl-3-propionyl-2-oxazolidinone 
• 107-02-8 acrolein 
• 90719-27-0 (S)-3-acryloyl-4-benzyloxazolidin-2-one 

Downstream Products

• 1408320-10-4 (S)-4-benzyl-3-((2S,3R)-3-(methoxymethoxy)-2-methylpent-4-enoyl)oxazolidin-2-one 
• 1262138-02-2 (4R,5S,6R,Z)-5-hydroxy-6-methoxy-2,4-dimethylocta-2,7-dienyl hept-6-enoate 
• 1262137-93-8 (2R,3S,4R)-3,5-bis((tert-butyldimethylsilyl)oxy)-1-((4-methoxybenzyl)oxy)-4-methylpentan-2-ol 
• 1262137-92-7 (2R,3S,4R)-3-((tert-butyldimethylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2-methylpentane-1,4-diol 
• 1262137-91-6 (3S,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((4-methoxybenzyl)oxy)methyl)-3-methyldihydrofuran-2(3H)-one 
• 144467-91-4 <2Z,4E,6E,8E,10S,11S,12R,13R,15R,15(2S,3S,5S,7R,8R,9S)>-15-<9-(tert-butyldimethylsiloxy)-7-<2-(tert-butyldimethylsiloxy)ethyl>-3--4,4,8-trimethyl-1,6-dioxaspiro<4.5>dec-2-yl>-11,13-bis(tert-butyldimethylsiloxy)-15-methoxy 
• 144467-93-6 <2Z,4E,6E,8E,10S,11S,12R,13R,15R,15(2S,3S,5S,7R,8R,9S)>-15-<9-(tert-butyldimethylsiloxy)-7-(2-oxoethyl)-3--4,4,8-trimethyl-1,6-dioxaspiro<4.5>dec-2-yl>-11,13-bis(tert-butyldimethylsiloxy)-15-methoxy-3,7,8,10,12-pentamethy 
• 144467-92-5 <2Z,4E,6E,8E,10S,11S,12R,13R,15R,15(2S,3S,5S,7R,8R,9S)>-15-<9-(tert-butyldimethylsiloxy)-7-(2-hydroxyethyl)-3--4,4,8-trimethyl-1,6-dioxaspiro<4.5>dec-2-yl>-11,13-bis(tert-butyldimethylsiloxy)-15-methoxy-3,7,8,10,12-pentam 

Relevant articles and documents

Studies toward the total synthesis of Cytospolide E

In this manuscript, we describe various approaches that we have examined towards the total synthesis of Cytospolide E. We initially attempted the RCM approach employing first and second generation Grubbs and Grubbs-Hoyeda catalysts resulting in the exclus

Direct Entry to 4,10-Didesmethyl (9S)-Dihydroerythronolide A via Catalytic Allene Osmylation

Desmethyl erythronolides have emerged as macrolide targets that may prove effective against resistant bacteria. A five-step sequence to 4,10-didesmethyl (9S)-dihydroerythronolide A (1) from known cyclic bis[allene] 13 is reported. Key structural and mechanistic aspects of the synthesis are discussed along with catalytic allene osmylation. An improved route to 13 is also described.

The first stereoselective total synthesis of the Z-isomer of cytospolide e

A convergent and highly stereoselective total synthesis of the Z-isomer of cytospolide E has been achieved via Evan's aldol reaction, Sharpless kinetic resolution and RCM cyclisation.