1383617-02-4

Basic information

• Product Name: 3,5-dimethoxybenzyl-N-succinimidyl carbonate
• Synonyms: 3,5-dimethoxybenzyl-N-succinimidyl carbonate
• CAS NO: 1383617-02-4
• Molecular Weight: 309.276
• Mol File: 1383617-02-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-dimethoxybenzyl-N-succinimidyl carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dimethoxybenzyl-N-succinimidyl carbonate(1383617-02-4)
• EPA Substance Registry System: 3,5-dimethoxybenzyl-N-succinimidyl carbonate(1383617-02-4)

Safety Data

• Hazardous Substances Data: 1383617-02-4(Hazardous Substances Data)

Upstream product

• 74124-79-1 di(succinimido) carbonate 
• 705-76-0 3,5-dimethoxybenzyl alcohol 

Relevant articles and documents

Synthesis and evaluation of novel caged DNA alkylating agents bearing 3,4-epoxypiperidine structure

Previously, we reported that the 3,4-epoxypiperidine structure, whose design was based on the active site of DNA alkylating antitumor antibiotics, azinomycins A and B, possesses prominent DNA cleavage activity. In this report, novel caged DNA alkylating agents, which were designed to be activated by UV irradiation, were synthesized by the introduction of four photo-labile protecting groups to a 3,4-epoxypiperidine derivative. The DNA cleavage activity and cytotoxicity of the caged DNA alkylating agents were examined under UV irradiation. Four caged DNA alkylating agents showed various degrees of bioactivity depending on the photosensitivity of the protecting groups.