137862-87-4 Usage
Description
Valsartan, also known as ent-Valsartan, is the (R)-enantiomer of Valsartan (V095750). It is a white to off-white solid with specific chemical properties that make it useful in various applications.
Uses
Used in Pharmaceutical Industry:
Valsartan is used as an active pharmaceutical ingredient for the treatment of hypertension (high blood pressure). It functions as an angiotensin II receptor blocker, which helps in relaxing blood vessels and reducing blood pressure.
Used in Cardiovascular Applications:
In the field of cardiology, valsartan is utilized as a therapeutic agent for the management of heart failure and post-myocardial infarction (heart attack). Its ability to block angiotensin II receptors aids in improving heart function and reducing the risk of further cardiovascular events.
Used in Research and Development:
Valsartan is also used as a research compound in the development of new drugs and therapies related to hypertension and cardiovascular diseases. Its chemical properties and mechanism of action provide valuable insights for scientists working on novel treatments for these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 137862-87-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,8,6 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 137862-87:
(8*1)+(7*3)+(6*7)+(5*8)+(4*6)+(3*2)+(2*8)+(1*7)=164
164 % 10 = 4
So 137862-87-4 is a valid CAS Registry Number.
InChI:InChI=1/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m1/s1
137862-87-4Relevant articles and documents
A PROCESS FOR THE PREPARATION OF HIGHLY PURE VALSARTAN
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Page/Page column 11-16, (2021/06/11)
Disclosed herein is a process for the preparation and purification of Valsartan. The process according to the invention is capable of removing the toxic nitroamine impurities and providing substantially pure Valsartan.
Valsartan without genotoxic impurity and preparation method thereof (by machine translation)
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, (2020/05/09)
To, valsartan crude: is cyclised to obtain valsartan medoxomil (V), and the valsartan crude product (IV), is purified to obtain valsartan medoxomil (III), to obtain valsartan medoxomil (,) through hydrolysis pH, modulation (II), to obtain the valsartan crude product. pH. The valsartan crude product is obtained by cyclizing the valsartan medoxomil sodium, into salt to obtain valsartan medoxomil,and preparation method of the valsartan medoxomil prepared by the following steps N,N - refining to obtain valsartan medoxomil and, N,N -% of valsartan medoxomil. (by machine translation)