13627-28-6 Usage
Description
2-chloro-N-(2-chloroethyl)acetamide, a chloroacetamide compound with the molecular formula C4H8Cl2NO, is a white to light brown solid. It is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, featuring a chloroethyl group attached to the nitrogen atom of the acetamide moiety. This moderately reactive compound necessitates careful handling to avoid skin and eye irritation and to minimize environmental risks due to its potential release.
Uses
Used in Pharmaceutical Industry:
2-chloro-N-(2-chloroethyl)acetamide is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 2-chloro-N-(2-chloroethyl)acetamide serves as a key intermediate in the production of agrochemicals, aiding in the creation of pesticides and other agricultural chemicals to enhance crop protection and yield.
Both applications highlight the importance of 2-chloro-N-(2-chloroethyl)acetamide as a versatile building block in chemical synthesis, underlining the need for proper handling and disposal to ensure safety and environmental sustainability.
Check Digit Verification of cas no
The CAS Registry Mumber 13627-28-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,6,2 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13627-28:
(7*1)+(6*3)+(5*6)+(4*2)+(3*7)+(2*2)+(1*8)=96
96 % 10 = 6
So 13627-28-6 is a valid CAS Registry Number.
13627-28-6Relevant articles and documents
THE CONDENSATION REACTION BETWEEN ISOCYANATES AND CARBOXYLIC ACIDS. A PRACTICAL SYNTHESIS OF SUBSTITUTED AMIDES AND ANILIDES.
Blagbrough, Ian S.,Mackenzie, Neil E.,Ortiz, Claudio,Scott, A. Ian
, p. 1251 - 1254 (2007/10/02)
Addition of a carboxylic acid to an isocyanate initially yields the mixed acid anhydride, decarboxylation of which leads to the N-substituted amide.The conversion of acid into amide was shown to proceed similarly for both aliphatic and aromatic carboxylic acids with a range of substituted isocyanates.