135963-42-7 Usage
Description
(R,S)-1-<2-<2-(3-methoxyphenyl)ethyl>phenoxy>-3-(dimethylamino)-2-propanol is a complex organic compound that consists of a mixture of both R and S enantiomers. It features a phenoxy group, a dimethylamino group, and a 3-methoxyphenyl ethyl group, all connected to a 2-propanol backbone. (R,S)-1-<2-<2-(3-methoxyphenyl)ethyl>phenoxy>-3-(dimethylamino)-2-propanol is significant for its stereoisomeric properties, which make it valuable in the study of stereochemistry and chiral resolution methods. It also exhibits unique solvent properties in various organic reactions and processes.
Uses
Used in Organic Synthesis:
(R,S)-1-<2-<2-(3-methoxyphenyl)ethyl>phenoxy>-3-(dimethylamino)-2-propanol is used as a chiral auxiliary in organic synthesis, providing a structural framework that aids in the creation of chiral molecules with specific configurations.
Used in Pharmaceutical Production:
(R,S)-1-<2-<2-(3-methoxyphenyl)ethyl>phenoxy>-3-(dimethylamino)-2-propanol serves as a starting material for the production of pharmaceuticals, leveraging its unique structural features to contribute to the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
(R,S)-1-<2-<2-(3-methoxyphenyl)ethyl>phenoxy>-3-(dimethylamino)-2-propanol is utilized as a reagent in chemical research, where its stereoisomeric properties and unique solvent behavior are harnessed to study and understand various chemical reactions and processes.
Used in Stereochemistry Studies:
(R,S)-1-<2-<2-(3-methoxyphenyl)ethyl>phenoxy>-3-(dimethylamino)-2-propanol is employed in the field of stereochemistry to investigate the effects of stereoisomerism on the properties and reactivity of molecules, as well as to develop methods for chiral resolution and the synthesis of enantiomerically pure compounds.
Used in Solvent Applications:
Due to its unique solvent properties, (R,S)-1-<2-<2-(3-methoxyphenyl)ethyl>phenoxy>-3-(dimethylamino)-2-propanol can be used in various organic reactions and processes where specific solvent characteristics are required to facilitate or enhance the reaction outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 135963-42-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,9,6 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 135963-42:
(8*1)+(7*3)+(6*5)+(5*9)+(4*6)+(3*3)+(2*4)+(1*2)=147
147 % 10 = 7
So 135963-42-7 is a valid CAS Registry Number.
135963-42-7Relevant articles and documents
Synthesis method of 2-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy)propyl-1-ol
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Paragraph 0025-0057, (2020/08/27)
The invention discloses a synthesis method of 2-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy) propyl-1-ol, and belongs to the field of organic chemical synthesis. According to the synthesis method, 2-((2-(3-methoxyphenethyl)phenoxy)methyl)ethylene oxi
Process for preparing sand Greythe ester is new hydrochloric acid
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Paragraph 0018; 0022; 0026, (2018/07/10)
The present invention discloses a preparation method of sarpogrelate hydrochloride. According to the preparation method, 2-[2-(3-methoxyphenyl)ethyl]phenol is adopted as a starting reactant, benzyl triethylammonium chloride is adopted as a phase transfer catalyst, the starting reactant, the phase transfer catalyst and epichlorohydrin form an ether in toluene and water, dimethylamine is adopted to carry out aminolysis in a pressurization reactor after the ether is formed to obtain 1-dimethylamino-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]-2-propanol, the 1-dimethylamino-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]-2-propanol and succinic anhydride are subjected to esterification in acetone, hydrogen chloride gas is directly introduced without recovery and replacement of the solvent to form a hydrochloride, and re-crystallization with acetone is performed to obtain the sarpogrelate hydrochloride refined product, wherein the purity is more than 99%.
Syntheses and Platelet Aggregation Inhibitory and Antithrombotic Properties of ethyl>benzenes
Kikumoto, Ryoji,Hara, Hiroto,Ninomiya, Kunihiro,Osakabe, Masanori,Sugano, Mamoru,et al.
, p. 1818 - 1823 (2007/10/02)
A series of ethyl>benzene derivatives were synthesized and evaluated for their ability to inhibit collagen-induced platelet aggregation in vitro and to protect experimantal thrombosis in mice.The results showed that the compounds were in vitro inhibitors of collagen-induced platelet aggregation.Most of them were also effective in the mouse antithrombotic assay.The compounds were found to be potent antagonists to S2 serotonergic receptor, and good correlation (r = 0.85) between their S2 serotonergic receptor antagonism and their potency as platelet antiaggregatory drugs was observed.Among the compounds studied, monophenoxy>methyl>ethyl>succinate hydrochloride (12b, MCI-9042) was selected for further pharmacological and toxicological evaluation.
