1357262-40-8

Basic information

• Product Name: (S)-2-(((methyldiphenylsilyl)oxy)di(naphthalen-2-yl)methyl)pyrrolidine
• Synonyms: (S)-2-(((methyldiphenylsilyl)oxy)di(naphthalen-2-yl)methyl)pyrrolidine
• CAS NO: 1357262-40-8
• Molecular Weight: 549.788
• Mol File: 1357262-40-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-(((methyldiphenylsilyl)oxy)di(naphthalen-2-yl)methyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(((methyldiphenylsilyl)oxy)di(naphthalen-2-yl)methyl)pyrrolidine(1357262-40-8)
• EPA Substance Registry System: (S)-2-(((methyldiphenylsilyl)oxy)di(naphthalen-2-yl)methyl)pyrrolidine(1357262-40-8)

Safety Data

• Hazardous Substances Data: 1357262-40-8(Hazardous Substances Data)

Upstream product

• 144-79-6 chloromethyldiphenylsilane 
• 130798-48-0 (S)-(-)-α,α-di(2-naphthyl)-2-pyrrolidinemethanol 

Relevant articles and documents

Mukaiyama-Michael reactions with acrolein and methacrolein: A catalytic enantioselective synthesis of the C17-C28 fragment of pectenotoxins

Enantioselective iminium-catalyzed reactions with acrolein and methacrolein are rare. A catalytic enantioselective Mukaiyama-Michael reaction that readily accepts acrolein or methacrolein as substrates, affording the products in good yields and 91-97% ee, is presented. As an application of the methodology, an enantioselective route to the key C17-C28 segment of the pectenotoxin using the Mukaiyama-Michael reaction as the key step is described.