13532-77-9

Basic information

• Product Name: 5-AMINO-2,2-DIMETHYLPENTANOL
• Synonyms: 5-Amino-2,2-dimethyl-1-pentanol;TIMTEC-BB SBB007685;5-AMINO-2,2-DIMETHYL-PENTAN-1-OL;5-AMINO-2,2-DIMETHYLPENTANOL;2,2-DIMETHYL-5-AMINO-1-PENTANOL;ASINEX-REAG BAS 07648341;5-Hydroxy-4,4-dimethylpentylamine;5-Amino-2,2-dimethylpentanol 98%
• CAS NO: 13532-77-9
• Molecular Formula: C₇H₁₇NO
• Molecular Weight: 131.22
• Product Categories: Amino Alcohols;Organic Building Blocks;Oxygen Compounds
• Mol File: 13532-77-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 239.4 °C at 760 mmHg
• Flash Point: 228 °F
• Appearance: /
• Density: 0.903 g/cm³
• Vapor Pressure: 0.00706mmHg at 25°C
• PKA: 15.19±0.10(Predicted)
• CAS DataBase Reference: 5-AMINO-2,2-DIMETHYLPENTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-2,2-DIMETHYLPENTANOL(13532-77-9)
• EPA Substance Registry System: 5-AMINO-2,2-DIMETHYLPENTANOL(13532-77-9)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36-43
• Safety Statements: 26-37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 13532-77-9(Hazardous Substances Data)

Usage

Description

5-AMINO-2,2-DIMETHYLPENTANOL is an organic compound with the molecular formula C7H17NO. It is a colorless to pale yellow liquid with a mild, sweet odor. 5-AMINO-2,2-DIMETHYLPENTANOL is characterized by the presence of an amino group (-NH2) and two methyl groups (-CH3) attached to the second carbon atom of a pentanol (five-carbon alcohol) backbone. Its unique structure endows it with versatile reactivity and potential applications in various industries.

Uses

Used in Pharmaceutical Industry:
5-AMINO-2,2-DIMETHYLPENTANOL is used as a reactant for the synthesis of various pharmaceutical compounds. Its ability to undergo reductive amination with borohydride and borane reducing agents allows for the creation of complex molecules with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 5-AMINO-2,2-DIMETHYLPENTANOL is used as a reactant for copper-catalyzed Nand O-arylation with aryl iodides. This reaction enables the formation of new carbon-nitrogen and carbon-oxygen bonds, which are essential for the development of a wide range of organic compounds.
Used in Catalyst Preparation:
5-AMINO-2,2-DIMETHYLPENTANOL is used in the preparation of N-(alkyl)arylamine derivatives via a selective room-temperature carbon-nitrogen coupling reaction. The use of copper iodide as a catalyst and diketone as a ligand allows for the efficient synthesis of these derivatives, which can be utilized in various applications, including the development of new materials and pharmaceuticals.

InChI:InChI=1/C7H17NO/c1-7(2,6-9)4-3-5-8/h9H,3-6,8H2,1-2H3/p+1

Upstream product

• 25252-68-0 4,4-dimethyl-5-hydroxyvaleronitrile 

Downstream Products

• 1419258-61-9 1,3-diphenyl-(5-thiophen-3-yl)-4,5-dihydro-1H-pyrazole-4-carboxylic acid (5-hydroxy-4,4-dimethylpentyl)amide 
• 1419258-69-7 3-(4-fluoro-phenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole-4-carboxylic acid (5-hydroxy-4,4-dimethyl-pentyl)-amide