1343-88-0 Usage
Description
Magnesium silicate is a synthetic, usually amorphous, white powder that is insoluble in water and alcohol. It has a molar ratio of silicon dioxide to magnesium oxide of approximately 2.2 to 3.3 and is characterized by its odorless and tasteless properties. It is commonly used as an anticaking agent, processing aid, and adsorbent in various industries.
Uses
Used in Food Industry:
Magnesium silicate is used as an anti-caking agent, filter aid, coating agent, candy polishing glaze, chewing gum base powder, and rice coating agent. It helps in the processing of beverages, food products, and pharmaceuticals by removing protein/tannin complex constituents through surface area and adsorptive effects.
Used in Pharmaceutical Industry:
Magnesium silicate is used as an antacid to neutralize stomach acid and alleviate indigestion and heartburn.
Used in Chemical Analysis:
Magnesium silicate is used for organic chlorine residue analysis and as a polyether adsorbent, with the role of adsorption and decolorization.
Used in Chromatography:
Magnesium silicate, in the form of Florisil, is used as a column packing material in column chromatography, an adsorbent in gas chromatography with electron capture detector (GC/ECD), capillary column chromatography, and adsorption column chromatography. It is also used in clean-up procedures in gas chromatography-tandem mass spectrometry and GC-FID.
Used in Earth Sciences:
Magnesium silicate is very important in the earth sciences because it is the material that makes up most of the volume of the Earth. It can be prepared by calcining the oxide with silica, SiO2, at an elevated temperature.
Identification test
500 mg of sample was mixed with 10 ml of dilute hydrochloric acid test solution (TS-117), filtered and neutralized with ammonia test solution (TS-13) on litmus paper. The filtrate after neutralization was positive after the magnesium test (IT-21).
With platinum wire ring dipped in several ammonium phosphate crystals, melting in the colorless flame on the ball, dipped in the sample when it is hot, and then melt, the silica was floating on the surface of the ball. Having been put cold, it turns into an opaque small ball with reticular structure. Indicating that the silicon test is positive.
Solubility: insoluble in water and ethanol (OT-42);
easily decomposed in inorganic acid.
The pH of the 10% slurry was 7.0 to 10.8.
Content analysis
Analysis of the content of magnesium oxide: weigh about 1.5g sample exactly; take it into a 250ml conical flask; add 1mol/L sulfuric acid 50.0ml, in the steam bath for 1h. Cool to ambient temperature; add one drop of methyl orange test solution (TS-148), and the excess acid is titrated with 1 mol/L sodium hydroxide solution. 1mol/L sulfuric acid per milliliter is equivalent to MgO2 0.15mg.
Analysis of silica content: took about 700mg sample, weighed to 0.1mg; took it into a 150ml beaker; added 20ml 1mol/L sulfuric acid, heating in the steam bath for 1.5h; decant the supernatant, and filter it with sterile filter paper; then the residue should be washed with hot water 3 times in the beaker, and pass through the filter paper. The residue was impregnated with 25 ml of water and digested on a steam bath for 15 min. Finally, the residue was transferred to the filter paper and rinsed with hot water onto the filter paper. The filter paper and filter residue was removed into the platinum crucible. Heated to dry and burn, and then it underwent a strong burning for 30min, cooling and weighing. Wet the residue with water. 6ml of hydrofluoric acid and 3 drops of sulfuric acid was added. Evaporated to dry, and then it would stand a 5min burning, weighing after cooling. The weight lost by the sample is the weight of SiO2.
Toxicity
ADI values are not subject to special provisions (FAO/WHO, 2001).
GRAS (FDA, § 182.2437, 2000).
Maximal level??? FAO/WHO (1984, g/kg): powdered dairy products (milk powder, cream powder, high fat milk powder, semi-cream powder) 10 (alone or in combination with other anti-agent, only for vending machines); powdered sugar for coating and glucose powder 15, but no starch included.
Production Methods
Magnesium silicate may be prepared from sodium silicate and
magnesium sulfate. The silicate also occurs in nature as the minerals
meerschaum, parasepiolite, and sepiolite.
Hazard
Toxic by inhalation, use in foods restricted
to 2%.
Pharmaceutical Applications
Magnesium silicate is used in oral pharmaceutical formulations and
food products as a glidant and an anticaking agent.
Safety
Magnesium silicate is used in oral pharmaceutical formulations and
is generally regarded as an essentially nontoxic and nonirritant
material.
Orally administered magnesium silicate is neutralized in the
stomach to form magnesium chloride and silicon dioxide; some
magnesium is absorbed. Caution should be used when greater than
50 mEq of magnesium is given daily to persons with impaired renal
function, owing to the risk of hypermagnesemia.
Reported adverse effects include the formation of bladder and
renal calculi following the regular use, for many years, of
magnesium silicate as an antacid.
Check Digit Verification of cas no
The CAS Registry Mumber 1343-88-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,3,4 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1343-88:
(6*1)+(5*3)+(4*4)+(3*3)+(2*8)+(1*8)=70
70 % 10 = 0
So 1343-88-0 is a valid CAS Registry Number.
InChI:InChI=1/Mg.O3Si/c;1-4(2)3/q+2;-2