134-58-7 Usage
Description
8-Azaguanine, also known as a triazolopyrimidine, is a purine analogue derived from 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively. It is characterized by its yellow powder appearance and exhibits antineoplastic activity, making it a promising compound for various applications in the pharmaceutical and medical industries.
Uses
Used in Antineoplastic Applications:
8-Azaguanine is used as an antineoplastic agent for its ability to inhibit cancer cell growth and proliferation. It functions as a purine antimetabolite, interfering with the synthesis of nucleic acids and proteins in cancer cells, thereby exerting its antineoplastic effects.
Used in Pharmaceutical Industry:
8-Azaguanine is used as a key component in the development of novel drugs and drug delivery systems targeting various types of cancer. Its antineoplastic properties make it a valuable asset in the creation of innovative cancer treatments and therapies.
Used in Research and Development:
8-Azaguanine is utilized as a research tool in the study of cancer biology, cell metabolism, and the development of new cancer therapies. Its unique chemical properties and antineoplastic activity allow researchers to explore its potential in various experimental settings and preclinical models.
Hazard
Mitotoic poison.
Purification Methods
Dissolve it in hot M NH4OH, filter, and cool. Recrystallise it, and wash it with water, then dry it in a vacuum. [Beilstein 26 III/IV 4171.]
Check Digit Verification of cas no
The CAS Registry Mumber 134-58-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 134-58:
(5*1)+(4*3)+(3*4)+(2*5)+(1*8)=47
47 % 10 = 7
So 134-58-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h1H,(H3,5,6,7,8,9,11)
