1338-39-2

Basic information

• Product Name: Span 20
• Synonyms: EmulsifierS20;radiasurf7125;Arlasel 20 ;Sorbitan Monolaurate (Span-20);Span #20 (Sorbitan monolaurate);span (R) 20 hlb-value 8.6;span(R) 20 solution;Span(rg 20
• CAS NO: 1338-39-2
• Molecular Formula: C18H34O6
• Molecular Weight: 346.46
• EINECS: 215-663-3
• Product Categories: Ester Type (Surfactants);Functional Materials;Nonionic Surfactants;Surfactants;Cosmetic Ingredients & Chemicals
• Mol File: 1338-39-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 401.18°C (rough estimate)
• Flash Point: >230 °F
• Appearance: light yellow viscous liquid
• Density: 1.032 g/mL at 25 °C(lit.)
• Vapor Pressure: 8.23E-13mmHg at 25°C
• Refractive Index: n20/D 1.474(lit.)
• Storage Temp.: Store below +30°C.
• Solubility: Practically insoluble, but dispersible in water, miscible with alcohol.
• Water Solubility: Soluble in 2-ethoxyethanol, ethanol and methanol. Not miscible or difficult to mix in water.
• Merck: 14,8724
• CAS DataBase Reference: Span 20(CAS DataBase Reference)
• NIST Chemistry Reference: Span 20(1338-39-2)
• EPA Substance Registry System: Span 20(1338-39-2)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 1
• RTECS: WG2920000
• F: 10-23
• TSCA: Yes
• Hazardous Substances Data: 1338-39-2(Hazardous Substances Data)

Usage

Description

Span 20, also known as Sorbitan monolaurate, is a co-surfactant that belongs to the sorbitan ester family. It is a brownish-yellow, viscous liquid with unique properties that make it suitable for various applications across different industries. As a co-surfactant, Span 20 aids in stabilizing emulsions and improving the solubility of certain substances.

Uses

Used in Pharmaceutical Industry:
Span 20 is used as a co-surfactant for enhancing solubility and oral bioavailability of drugs like itraconazole. It helps in improving the drug's absorption and effectiveness when administered orally.
Used in Cosmetics Industry:
Span 20 is used as an emulsifier in cosmetic creams and lotions, such as Lonzest(R) SML, to create stable oil-in-water emulsions. It also acts as a stabilizer for essential oils in water, ensuring a uniform distribution of the oil phase throughout the product.
Used in Food Industry:
Sorbitan monolaurate, a form of Span 20, is used as a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol. It helps in creating stable emulsions and improving the texture of various food products.
Used in Chemical Research:
Span 20 has been utilized in studies to investigate the oxidation of unsaturated lipids in oil-in-water emulsions. Its role as a co-surfactant allows for better understanding of the emulsion's stability and the factors affecting lipid oxidation.

Safety Profile

Slightly toxic by ingestion. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

InChI:InChI=1/C18H34O6/c1-2-3-4-5-6-7-8-9-10-11-16(21)23-13-15(20)18-17(22)14(19)12-24-18/h14-15,17-20,22H,2-13H2,1H3/t14-,15+,17+,18?/m0/s1

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Combination of Span 20 (cas 1338-39-2) and pH-assisted walnut oil extraction during aqueous extraction process08/30/2019

To destabilize the emulsion during aqueous extraction processing (AEP) and improve oil yield of walnuts, sugar-aided aqueous extraction (SAAE) with optimized extraction parameters was explored. Demulsification mechanism using Span 20 at acidic pH during SAAE was discovered. Highest walnut oil yi...detailed