1334392-87-8

Basic information

• Product Name: C₂₄H₂₂ClF₃N₂O₃
• CAS NO: 1334392-87-8
• Molecular Weight: 478.898
• Mol File: 1334392-87-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₂ClF₃N₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₂ClF₃N₂O₃(1334392-87-8)
• EPA Substance Registry System: C₂₄H₂₂ClF₃N₂O₃(1334392-87-8)

Safety Data

• Hazardous Substances Data: 1334392-87-8(Hazardous Substances Data)

Upstream product

• 873203-36-2 1-bromo-4-[4-(trifluoromethoxy)phenoxy]benzene 
• 958457-41-5 (4-(4-(trifluoromethoxy)phenoxy)phenyl)boronic acid 
• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 
• 1506-67-8 3-hydroxy-6-hydroxymethyl-2-methyl-pyran-4-one 
• 958457-33-5 6-Hydroxymethyl-2-methyl-3-trifluoromethanesulfonyloxy-pyran-4(1H)-one 
• 958457-34-6 6-hydroxymethyl-2-methyl-3-(4-{4-[(trifluoromethyl)oxy]phenyl}oxy)-pyran-4(1H)-one 
• 958457-36-8 6-hydroxymethyl-2-methyl-3-(4-{4-[(trifluoromethyl)oxy]phenyl}oxy)-pyridinone 
• 2029-49-4 2,6-dihydroxymethyl-3-hydroxy-4-pyrone 
• 106-41-2 4-bromo-phenol 
• 103962-05-6 1-iodo-4-(trifluoromethoxy)benzene 

Relevant articles and documents

Potent antimalarial 4-pyridones with improved physico-chemical properties

Antimalarial 4-pyridones are a novel class of inhibitors of the plasmodial mitochondrial electron transport chain targeting Cytochrome bc1 (complex III). In general, the most potent 4-pyridones are lipophilic molecules with poor solubility in aqueous medi