133164-11-1Relevant articles and documents
Benzofuran and coumarin derivatives from the root of Angelica dahurica and their PPAR-γ ligand-binding activity
Matsuo, Yukiko,Yamaguchi, Emi,Hakamata, Ryo,Ootomo, Kanae,Takatori, Kazuhiro,Fukaya, Haruhiko,Mimaki, Yoshihiro
, (2020/02/26)
A phytochemical investigation of the root of Angelica dahurica led to the isolation of benzofuran and coumarin derivatives. This is the first report of the isolation and identification of three furanocoumarin sulfates from A. dahurica root. The structures of a total of twelve undescribed compounds were determined by extensive spectroscopic analysis, including 2D NMR data, hydrolysis, and solvolysis, followed by either physicochemical and spectroscopic data or X-ray crystallographic analysis. The isolated compounds were evaluated for their PPAR-γ ligand-binding activity, and six compounds showed significant PPAR-γ ligand-binding activity. In particular, the undescribed benzofuran derivative, 3-[6,7-furano-9-hydroxy-4-(2″,3″-dihydroxy-3″-methylbutyloxy)]-phenyl propionic acid, exhibited the most potent PPAR-γ ligand-binding activity and accumulated intracellular lipid in 3T3-L1 cells.
Nonvolatiles of commercial lime and grapefruit oils separated by high-speed countercurrent chromatography
Feger, Wolfgang,Brandauer, Herbert,Gabris, Paulina,Ziegler, Herta
, p. 2242 - 2252 (2007/10/03)
The nonvolatile fractions of cold-pressed peel oils of Key and Persian lime as well as grapefruit were separated by high-speed countercurrent chromatography (HS-CCC). In addition to the isolation of the main coumarins, psoralens and polymethoxyflavones, a
STEROIDS, CHROMONE AND COUMARINS FROM ANGELICA OFFICINALIS
Harkar, S.,Razdan, T. K.,Waight, E. S.
, p. 419 - 426 (2007/10/02)
From the ethyl acetate extract of the fresh roots of Angelica officinalis var. himaliaca, besides sitosterol, pregnenolone, peucenin-7-methyl ether, osthol and 18 furanocoumarins have been characterized by spectroscopic methods, including 13C NMR, and some chemical transformations. - Keywords: Angelica officinalis; Umbelliferae; root; pregnenolone; sitosterol; osthol; peucenin-7-methyl ether; furanocoumarins.