132046-98-1

Basic information

• Product Name: 5-O-(Trimethylsilyl)-6,7-O-isopropylidene-2,3-dideoxy-D-arabino-hept-2-enono-1,4-lactone
• Synonyms: 5-O-(Trimethylsilyl)-6,7-O-isopropylidene-2,3-dideoxy-D-arabino-hept-2-enono-1,4-lactone
• CAS NO: 132046-98-1
• Molecular Weight: 286.4
• Mol File: 132046-98-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-O-(Trimethylsilyl)-6,7-O-isopropylidene-2,3-dideoxy-D-arabino-hept-2-enono-1,4-lactone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-O-(Trimethylsilyl)-6,7-O-isopropylidene-2,3-dideoxy-D-arabino-hept-2-enono-1,4-lactone(132046-98-1)
• EPA Substance Registry System: 5-O-(Trimethylsilyl)-6,7-O-isopropylidene-2,3-dideoxy-D-arabino-hept-2-enono-1,4-lactone(132046-98-1)

Safety Data

• Hazardous Substances Data: 132046-98-1(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 61550-02-5 (furan-2-yloxy)-trimethylsilane 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 

Relevant articles and documents

Ascent of the Aldose Series by Four Carbon Atoms: Total Synthesis of D-glycero-D-talo-L-talo-Undecose Pentaacetonide

Enantiomerically pure undecose acetonide 9 was synthesized, through heptose intermediate 5, starting with D-glyceraldehyde acetonide (1).The key steps were two consecutive four-carbon homologations, each consisting of four reactions: (i) stereoselective elongation of the aldehyde precursor with 2-(trimethylsiloxy)furan, giving Cn+4 butenolide templates 2 and 6, (ii) anti-selective cis-dihydroxylation of the butenolide double bond, giving fully functionalized lactones 3 and 7, (iii) lactone ring opening and protection, giving open-chain methyl esters 4 and 8, and (iv) DIBAL reduction to aldoses 5 and 9.At the end of the eight-step sequence, undecose 9 was prepared in a 5.1percent overall yield, which corresponded to a 69.5percent average yield per step.