131444-94-5

Basic information

• Product Name: 5'-O-(4-Methoxytrityl)-2'-deoxyribosylurea-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
• CAS NO: 131444-94-5
• Molecular Weight: 648.739
• Mol File: 131444-94-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-(4-Methoxytrityl)-2'-deoxyribosylurea-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4-Methoxytrityl)-2'-deoxyribosylurea-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(131444-94-5)
• EPA Substance Registry System: 5'-O-(4-Methoxytrityl)-2'-deoxyribosylurea-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(131444-94-5)

Safety Data

• Hazardous Substances Data: 131444-94-5(Hazardous Substances Data)

Upstream product

• 50-89-5 thymidine 
• 14470-28-1 mono-4-methoxytrityl chloride 
• 42926-80-7 5'-O-(4-monomethoxytrityl)-2'-deoxythymidine 
• 131444-91-2 C₂₇H₂₈N₂O₆ 
• 102691-36-1 N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite 
• 131444-92-3 N-(5-O-monomethoxytrityl-2-deoxy-D-ribofuranosyl)-urea 

Relevant articles and documents

Insertion of the fragile 2'-deoxyribosylurea residue into oligodeoxynucleotides

Deoxyribosylurea is an alkali sensitive DNA defect induced by the action of ionizing radiation. Oligonucleotides bearing this residue were synthesized using 5'-O-(4-methoxytrityl)-2'-deoxyribosylurea-3'-O-(2-cyanoethyl-N,N'-dii sopropyl)phosphoramidite and PAC protected deoxynucleoside phosphoramidites.