1312942-15-6 Usage
Structure
Contains a pyrimidine ring and an aminoethyl group with a methoxy substituent
Type of compound
Boronic acid derivative
Usage
Used in organic synthesis as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds
Specific reactions
Particularly useful in Suzuki-Miyaura cross-coupling reactions for the construction of complex organic molecules
Applications
Building block for the synthesis of pharmaceuticals, agrochemicals, and materials science applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1312942-15-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,2,9,4 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1312942-15:
(9*1)+(8*3)+(7*1)+(6*2)+(5*9)+(4*4)+(3*2)+(2*1)+(1*5)=126
126 % 10 = 6
So 1312942-15-6 is a valid CAS Registry Number.
1312942-15-6Relevant articles and documents
Discovery of 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine as a Potent IKur Inhibitor
Finlay, Heather J.,Johnson, James A.,Lloyd, John L.,Jiang, Ji,Neels, James,Gunaga, Prashantha,Banerjee, Abhisek,Dhondi, Naveen,Chimalakonda, Anjaneya,Mandlekar, Sandhya,Conder, Mary Lee,Sale, Harinath,Xing, Dezhi,Levesque, Paul,Wexler, Ruth R.
, p. 831 - 834 (2016)
A new series of phenylquinazoline inhibitors of Kv 1.5 is disclosed. The series was optimized for Kv 1.5 potency, selectivity versus hERG, pharmacokinetic exposure, and pharmacodynamic potency. 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine (13k) was identified as a potent and ion channel selective inhibitor with robust efficacy in the preclinical rat ventricular effective refractory period (VERP) model and the rabbit atrial effective refractory period (AERP) model.
