131-10-2

Basic information

• Product Name: berbine
• Synonyms: (S)-5,8,13,13a-Tetrahydro-6H-dibenzo[a,g]quinolizine;(-)-Berbine;(S)-7,8,13,14-Tetrahydroprotoberberine;(S)-Tetrahydroprotoberberine;C05204;alpha-berbine
• CAS NO: 131-10-2
• Molecular Formula: C17H17N
• Molecular Weight: 235.32
• Mol File: 131-10-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 85-86 ºC
• Boiling Point: 354.2 °C at 760 mmHg
• Flash Point: 151.8 °C
• Appearance: /
• Density: 1.17
• Vapor Pressure: 3.41E-05mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: berbine(CAS DataBase Reference)
• NIST Chemistry Reference: berbine(131-10-2)
• EPA Substance Registry System: berbine(131-10-2)

Safety Data

• Hazardous Substances Data: 131-10-2(Hazardous Substances Data)

Usage

General Description

Berberine is a naturally occurring, bioactive alkaloid chemical found in various plants, including the barberry, tree turmeric, Oregon grape, and goldenseal. It has a broad range of medicinal properties and has been used in traditional Chinese and Ayurvedic medicine for centuries. It's primarily renowned for its potent anti-inflammatory and antibacterial effects, and recent scientific studies indicate that it may also help regulate blood sugar levels, manage cholesterol, and facilitate weight loss. Despite these potential benefits, it has certain side effects and can interact negatively with other medications.

InChI:InChI=1/C17H17N/c1-2-7-15-12-18-10-9-13-5-3-4-8-16(13)17(18)11-14(15)6-1/h1-8,17H,9-12H2/t17-/m0/s1

Upstream product

• 64-18-6 formic acid 
• 19716-56-4 (-)-1-benzyl-1,2,3,4-tetrahydro-isoquinoline 

Related news

The Polonovski–Potier Reaction of berbine (cas 131-10-2) N-Oxides. Synthesis of 8-Hydroxymethyl and 8-Methylberbine (cas 131-10-2)s09/27/2019

The Polonovski–Potier reaction of trans and cis berbines N-oxides was studied. The 8-cyano derivative obtained from transN-oxides were used to synthesize 8-hydroxymethyl and 8-methyl berbines. This procedure was applied to the stereocontroled synthesis of (8R, 14S)-(−)-8-methylcanadine from (14...detailed

Ilicifoline: new berbine (cas 131-10-2) dimer alkaloid from Berberis ilicifolia09/26/2019

From Berberis ilicifolia, a new dimer is described, but this alkaloid is related to a bisberbine. It is the first dimer of this type in Berberis.detailed

4-Methylenedioxolan-2-ones as convenient synthons for the preparation of natural products of the berbine (cas 131-10-2) and calycotomine series09/25/2019

Intramolecular amidoalkylation of nonactivated 3-(2-arylethyl)-4-hydroxyoxazolidin-2-ones in polyphosphoric acid gave oxazolo[4,3-a]isoquinolin-3-one whose hydrolysis affords isoquinoline β-amino alcohols, calycotomine analogs. Using the developed procedure, 13,13,13a-trimethylberbine was synth...detailed