1303507-75-6

Basic information

• Product Name: N-benzyloxy-α-methyl-α-bromopropionamide
• Synonyms: N-benzyloxy-α-methyl-α-bromopropionamide
• CAS NO: 1303507-75-6
• Molecular Weight: 272.142
• Mol File: 1303507-75-6.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: N-benzyloxy-α-methyl-α-bromopropionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyloxy-α-methyl-α-bromopropionamide(1303507-75-6)
• EPA Substance Registry System: N-benzyloxy-α-methyl-α-bromopropionamide(1303507-75-6)

Safety Data

• Hazardous Substances Data: 1303507-75-6(Hazardous Substances Data)

Upstream product

• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 622-33-3 N-benzyloxyamine 
• 20769-85-1 2-bromoisobutyric acid bromide 

Downstream Products

• 1303508-08-8 2-methyl-2-(2,2,2-trifluoroethoxy)-N-(phenylmethoxy)-propanamide 
• 60316-45-2 2-methyl-N-(phenylmethoxy)-2-propenamide 

Relevant articles and documents

Direct N- sec -Alkylation of Amides by Reaction of α-Halohydroxamates and Sulfonylindoles: An Approach to 3-Indolyl Methanamines

A catalyst-free, base-mediated N- sec -alkylation of amides by reaction of sulfonylindoles and α-halohydroxamates has been developed. The N- sec -alkylation of amides reaction is based on an intermolecular nucleophilic addition of vinylogous imine with N

Synthesis of 2-Aminoimidazolones and Imidazolones by (3 + 2) Annulation of Azaoxyallyl Cations

The first examples of (3 + 2) annulations between azaoxyallyl cations and cyanamides and nitriles to give the corresponding 2-aminoimidazolones and imidazolones are reported. On the basis of the isolation of unexpected imidate products with certain substr

Efficient one-pot synthesis of 1,3-dihydro-2H-pyrrol-2-one derivatives via aza-oxyallylic cations

An efficient synthesis of functionalized 1,3-dihydro-2H-pyrrol-2-one was developed based on a [3+2] cycloaddition reaction of aza-oxyallylic cations and alkynes. With this novel method, a variety of substituted alkynes were readily converted into their co

[3 + 2]-Cycloaddition of Azaoxyallyl Cations with 1,2-Benzisoxazoles: A Rapid Entry to Oxazolines

A novel and efficient [3 + 2] cycloaddition reaction of azaoxyallyl cations and 1,2-benzisoxazoles to give oxazoline derivatives has been developed. The transformation provides a rapid entry to functionalized oxazoline scaffolds under mild and transition-metal-free conditions, which will greatly expand the reaction types of heterocycle chemistry and pave the way for syntheses of bioactive compounds.

An efficient synthesis of oxazolines: Via a cascade reaction between azaoxyallyl cations and 1,2-benzisoxazoles

A formal [3 + 2] cycloaddition reaction between the C and O terminals of azaoxyallyl cations formed in situ and 1,2-benzisoxazoles has been realized. This one-pot cycloaddition method provided an effective and practical pathway to synthesize oxazoline in good yields under mild conditions. The title products exhibited unique fluorescence properties.