1301185-13-6

Basic information

• Product Name: 1-(2,6-dichlorophenyl)-1H-pyrazole-4-carboximidamide
• Synonyms: 1-(2,6-dichlorophenyl)-1H-pyrazole-4-carboximidamide
• CAS NO: 1301185-13-6
• Molecular Weight: 255.106
• Mol File: 1301185-13-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,6-dichlorophenyl)-1H-pyrazole-4-carboximidamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,6-dichlorophenyl)-1H-pyrazole-4-carboximidamide(1301185-13-6)
• EPA Substance Registry System: 1-(2,6-dichlorophenyl)-1H-pyrazole-4-carboximidamide(1301185-13-6)

Safety Data

• Hazardous Substances Data: 1301185-13-6(Hazardous Substances Data)

Upstream product

• 792953-01-6 5-amino-1-(2,6-dichlorophenyl)-1H-pyrazole-4-carbonitrile 
• 1301185-14-7 C₁₀H₅Cl₂N₃ 
• 50709-36-9 (2,6-dichlorophenyl)hydrazine monohydrochloride 

Relevant articles and documents

Synthesis and antileishmanial activity of new 1-aryl-1H-pyrazole-4- carboximidamides derivatives

Chemotherapy for leishmaniasis, diseases caused by protozoa of the genus Leishmania, remains inefficient in several treatments. So there is a need to search for new drugs. In this work, we have synthesized 1-aryl-1H-pyrazole-4- carboximidamides derivatives and evaluated antileishmanial activities in vitro, as well as cytotoxic effects. Structure-activity relationship (SAR) studies were carried out with all the compounds of the series. Compound 2 showed an activity profile that can be improved through medicinal chemistry strategies.