128914-47-6 Usage
Description
(±)17-HETE, also known as hydroxyeicosatetraenoic acid, is a racemic mixture of the (S)and (R)-enantiomers of a cytochrome P450 (CYP450) metabolite of arachidonic acid. It plays a crucial role in regulating electrolyte and fluid transport in the kidney, with the (S)-enantiomer exhibiting stereospecific effects on sodium transport.
Used in Pharmaceutical Industry:
(±)17-HETE is used as a research compound for studying the role of arachidonic acid metabolites in kidney function and their potential therapeutic applications in treating kidney-related disorders. The (S)-enantiomer of 17-HETE, in particular, has been found to inhibit proximal tubule ATPase activity by as much as 70% at a concentration of 2 μM, making it a valuable tool for investigating the underlying mechanisms of electrolyte and fluid transport regulation.
Check Digit Verification of cas no
The CAS Registry Mumber 128914-47-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,9,1 and 4 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 128914-47:
(8*1)+(7*2)+(6*8)+(5*9)+(4*1)+(3*4)+(2*4)+(1*7)=146
146 % 10 = 6
So 128914-47-6 is a valid CAS Registry Number.
InChI:InChI=1/C20H32O3/c1-2-16-19(21)17-14-12-10-8-6-4-3-5-7-9-11-13-15-18-20(22)23/h3,5-6,8-9,11-12,14,19,21H,2,4,7,10,13,15-18H2,1H3,(H,22,23)/b5-3-,8-6-,11-9-,14-12-
