128837-28-5

Basic information

• Product Name: 3,4-Bis(ethoxymethoxy)benzaldehyde
• Synonyms: 3,4-Bis(ethoxymethoxy)benzaldehyde
• CAS NO: 128837-28-5
• Molecular Formula: C₁₃H₁₈O₅
• Molecular Weight: 254.28
• Product Categories: Aliphatics;Aromatics;Aliphatics, Aromatics
• Mol File: 128837-28-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 380.1±42.0 °C(Predicted)
• Appearance: /
• Density: 1.115±0.06 g/cm3(Predicted)
• Solubility: Chloroform
• CAS DataBase Reference: 3,4-Bis(ethoxymethoxy)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Bis(ethoxymethoxy)benzaldehyde(128837-28-5)
• EPA Substance Registry System: 3,4-Bis(ethoxymethoxy)benzaldehyde(128837-28-5)

Safety Data

• Hazardous Substances Data: 128837-28-5(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Oil

Upstream product

• 139-85-5 3,4-dihydroxybenzaldehyde 
• 3188-13-4 ethyl chloromethyl ether 

Downstream Products

• 487-52-5 butein 
• 1528738-99-9 (E)-3-(3,4-diethoxymethoxy-2-methoxyphenyl)-1-(3,4-diethoxymethoxyphenyl)prop-2-en-1-one 
• 1528738-98-8 3,4, -di(ethoxymethoxy)acetophenone 
• 1528738-97-7 1-(3,4-diethoxymethoxyphenyl)ethanol 
• 128837-30-9 2'-Hydroxy-4',3,4-triethoxymethoxychalkone 
• 21913-99-5 2-(3,4-dihydroxyphenyl)-7-hydroxychroman-4-one 
• 4049-38-1 eriodictyol 

Relevant articles and documents

Synthetic method for piceatannol derivatives and pharmaceutical compounds containing the piceatannol derivatives

The piceatannol derivatives were easily synthesized using a Wittig-Horner reaction, a Colvin rearrangement and a Sonogashira reaction. According to the result of investigating the anti-inflammatory activity of compounds synthesized in RAW264.7 macrophages induced by LPS, compounds 6 to 8 showed remarkable activity at the concentration of 10 andmu;M, and a compound 7 (90.1%), a compound 8 (60.8%) and a compound 6 (55.2%) showed no cytotoxicity. The present invention aims to provide a method for efficiently synthesizing the piceatannol derivatives and to confirm the biological activity of synthesized piceatannol derivatives.COPYRIGHT KIPO 2017

Synthesis of licochalcone analogues with increased anti-inflammatory activity

Licohalcones have been reported to have various biological activities. However, most of licochalcones also showed cytotoxicity even though their versitile utilities. Licochalcones B and D, which have common substituents at aromatic ring B, are targeted to