127799-53-5

Basic information

• Product Name: 1-(benzylo×y)carbonyl-2-(t-butylo×y)carbonyl-1-Methylhydrazine
• Synonyms: 1-(benzylo×y)carbonyl-2-(t-butylo×y)carbonyl-1-Methylhydrazine;1-Benzyl 2-tert-butyl 1-Methylhydrazine-1,2-dicarboxylate
• CAS NO: 127799-53-5
• Molecular Formula: C₁₄H₂₀N₂O₄
• Molecular Weight: 280.3196
• Mol File: 127799-53-5.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(benzylo×y)carbonyl-2-(t-butylo×y)carbonyl-1-Methylhydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(benzylo×y)carbonyl-2-(t-butylo×y)carbonyl-1-Methylhydrazine(127799-53-5)
• EPA Substance Registry System: 1-(benzylo×y)carbonyl-2-(t-butylo×y)carbonyl-1-Methylhydrazine(127799-53-5)

Safety Data

• Hazardous Substances Data: 127799-53-5(Hazardous Substances Data)

Usage

Description

1-(benzyloxy)carbonyl-2-(t-butyloxy)carbonyl-1-Methylhydrazine is a complex organic chemical compound characterized by the presence of a benzyl group, a t-butyl group, and two carbonyl groups attached to a methylhydrazine molecule. 1-(benzylo×y)carbonyl-2-(t-butylo×y)carbonyl-1-Methylhydrazine serves as a versatile intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries, due to its unique structural features that influence reactivity and stability.

Uses

Used in Pharmaceutical Industry:
1-(benzyloxy)carbonyl-2-(t-butyloxy)carbonyl-1-Methylhydrazine is utilized as a key building block in the synthesis of various pharmaceuticals. Its unique structure allows for the development of potential drug candidates with specific therapeutic properties. The benzyl and t-butyl groups contribute to the compound's reactivity, enabling the formation of new chemical entities with desired pharmacological activities.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(benzyloxy)carbonyl-2-(t-butyloxy)carbonyl-1-Methylhydrazine serves as an essential component in the creation of novel agrochemicals. Its structural attributes make it a valuable precursor in the synthesis of compounds with pesticidal, herbicidal, or other agricultural applications. 1-(benzylo×y)carbonyl-2-(t-butylo×y)carbonyl-1-Methylhydrazine's versatility in organic synthesis facilitates the development of innovative agrochemicals to address various agricultural challenges.
Used in Chemical Synthesis:
1-(benzyloxy)carbonyl-2-(t-butyloxy)carbonyl-1-Methylhydrazine is employed as an intermediate in various chemical reactions, allowing for the formation of a wide range of organic compounds. Its presence in the molecule can influence the reactivity and stability of the resulting products, making it a crucial component in the synthesis of new materials and chemical entities.
Used in Drug Discovery:
Researchers actively explore the potential applications of 1-(benzyloxy)carbonyl-2-(t-butyloxy)carbonyl-1-Methylhydrazine in drug discovery. Its unique structural features and reactivity make it a promising candidate for the development of new therapeutic agents. 1-(benzylo×y)carbonyl-2-(t-butylo×y)carbonyl-1-Methylhydrazine's versatility in organic synthesis enables the creation of diverse drug candidates with potential applications in various medical fields.

Upstream product

• 200813-54-3 2-benzyloxycarbonyl-1-tert-butoxycarbonyl-2-methyl-1-(4-methylphenylsulfonyl)hydrazine 
• 200813-53-2 1-tert-butoxycarbonyl-1-tosyl-2-benzyloxycarbonylhydrazine 
• 200813-52-1 benzyl 2-tosylhydrazine-1-carboxylate 
• 287729-00-4 N-benzyl-N-tert-butyloxycarbonylaminophthalimide 
• 426840-24-6 N^α-(benzyloxycarbonyl)-N^β,N^β-bis(tert-butyloxycarbonyl)-N^α-methylhydrazine 
• 185456-32-0 1-benzyl-1,2,2-tris(tert-butoxycarbonyl)hydrazine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 37519-04-3 1-(benzyloxy)carbonyl-1-methylhydrazine 
• 287729-06-0 N-methyl-N-benzyloxycarbonylaminophthalimide 
• 287728-91-0 N-benzyloxycarbonylaminophthalimide 
• 5331-43-1 N-benzyloxycarbonyl-hydrazine 

Downstream Products

• 151988-40-8 (S)-2-(N'-tert-Butoxycarbonyl-N-methyl-hydrazinocarbonyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 220079-44-7 1-(benzyloxycarbonyl)-2-ethyl-1-methyl-2-[(trideuteromethyl)tosylcarbamoyl]hydrazine 
• 220079-71-0 N'-[Benzyl-(toluene-4-sulfonyl)-aminocarbonyl]-N-ethyl-N'-methyl-hydrazinecarboxylic acid tert-butyl ester 
• 220079-41-4 N'-Ethyl-N-methyl-N'-(toluene-4-sulfonylaminocarbonyl)-hydrazinecarboxylic acid benzyl ester 
• 220079-68-5 N-Ethyl-N'-methyl-N'-(toluene-4-sulfonylaminocarbonyl)-hydrazinecarboxylic acid tert-butyl ester 
• 220079-20-9 N'-Ethyl-N'-(4-fluoro-benzoyl)-N-methyl-hydrazinecarboxylic acid benzyl ester 
• 220079-16-3 N'-Ethyl-N-methyl-hydrazinecarboxylic acid benzyl ester 
• 220079-14-1 1-(benzyloxycarbonyl)-2-(tert-butoxycarbonyl)-2-ethyl-1-methylhydrazine 
• 127799-54-6 2-Methylhydrazinecarboxylic acid,1,1-dimethylethyl ester 

Relevant articles and documents

FACTOR XIA-INHIBITING PYRIDOBENZAZEPINE AND PYRIDOBENZAZOCINE DERIVATIVES

The invention relates to substituted pyridobenzazepine and pyridobenzazocine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CARDIOVASCULAR DISORDERS

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

Very efficient one-pot conversion of N-aminophthalimide derivatives into the corresponding N-amino-di-tert-butyl imidodicarbonates

The phthaloyl group can be efficiently converted in very mild conditions into bis-tert-butyloxycarbonyl group using MeNH2, then Boc2O/DMAP, in a one-flask protocol.