1276666-10-4

Basic information

• Product Name: tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate
• Synonyms: [2-[(5-Chloro-benzooxazol-2-yl)(3-oxobutyl)amino]ethyl]carbamic acid tert-butyl ester;tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate;Carbamic acid, N-[2-[(5-chloro-2-benzoxazolyl)(3-oxobutyl)amino]ethyl]-, 1,1-dimethylethyl ester
• CAS NO: 1276666-10-4
• Molecular Formula: C₁₈H₂₄ClN₃O₄
• Molecular Weight: 381.85386
• Mol File: 1276666-10-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 145-148℃
• Appearance: /
• CAS DataBase Reference: tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate(1276666-10-4)
• EPA Substance Registry System: tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate(1276666-10-4)

Safety Data

• Hazardous Substances Data: 1276666-10-4(Hazardous Substances Data)

Usage

General Description

Tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethylcarbamate is a complex chemical compound with a molecular structure that includes a tert-butyl functional group, a 5-chlorobenzo[d]oxazol-2-yl group, and a 3-oxobutylamino group. tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethylcarbamate is an ethylcarbamate derivative, which is a type of organic compound that contains a carbamate functional group. Ethylcarbamates are used in various chemical and pharmaceutical applications, including as intermediates in the synthesis of other compounds and as potential pharmacological agents. The specific properties and uses of tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethylcarbamate would depend on its exact chemical composition and structure, and further research would be necessary to fully understand its potential applications.

Upstream product

• 22876-19-3 5-chloro-2-mercaptobenzoxazole 
• 57260-73-8 N-BOC-1,2-diaminoethane 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 1276666-16-0 C₁₃H₁₆ClN₃O*C₁₈H₁₄O₈ 
• 1276666-14-8 C₁₃H₁₆ClN₃O*C₁₈H₁₄O₈ 
• 1030377-33-3 Suvorexant 

Relevant articles and documents

A [2 - [(5 - chloro - benzo oxazole - 2 - yl) (3 - oxo-butyl) amino] ethyl] carbamic acid tert-butyl preparation method (by machine translation)

The invention discloses a [2 - [(5 - chloro - benzo oxazole - 2 - yl) (3 - oxo-butyl) amino] ethyl] carbamic acid tert-butyl preparation method, in order to ethylenediamine, vinyl, 2 - amino - 4 - chlorophenol and the like as raw materials, after five-step reaction to obtain the target product [2 - [(5 - chloro - benzo oxazole - 2 - yl) (3 - oxo-butyl) amino] ethyl] tert-butyl carbamate. The invention has simple operation, environment friendly, comprehensive yield is 52% more, than the existing 35.6% yield, with a remarkable enhancement, greatly reduces the production cost of the existing drugs, is suitable for industrial scale production. (by machine translation)

Process for the preparation of an intermediate for an orexin receptor antagonist

The present invention is directed to processes for preparing an intermediate for a diazepane compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved.

PROCESS FOR THE PREPARATION OF AN OREXIN RECEPTOR ANTAGONIST

The present invention is directed to processes for preparing a diazepane compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is further directed to crystalline forms of this diazepane compound and pharmaceutical compositions thereof.