126705-22-4Relevant articles and documents
Convenient synthesis and isolation of 1-aminocyclopropane-1-carboxylic acid (ACC) and N-protected ACC derivatives
Allwein, Shawn P.,Secord, Elizabeth A.,Martins, Andrew,Mitten, Jeffrey V.,Nelson, Todd D.,Kress, Michael H.,Dolling, Ulf H.
, p. 2489 - 2492 (2004)
A convenient route to 1-aminocyclopropane-1-carboxylic acid (1, ACC) and N-protected derivatives was developed. This route utilizes a bisalkylation of an O-benzyl glycine derived imine followed by global deprotection via hydrogenation. Direct isolation of ACC from a non-aqueous stream or efficient conversion to N-protected derivatives in a single flask is described.
Solid-phase synthesis and utilization of side-chain reactive unnatural amino acids
O'Donnell, Martin J.,Alsina, Jordi,Scott, William L.
, p. 8403 - 8406 (2007/10/03)
Alkylation of the benzophenone imine of glycine Wang resin with α,ω-dihaloalkanes yielded valuable reactive intermediates. These racemic ω-chloro or ω-bromo intermediates were converted to α-amino acids containing diverse side-chain functionalities (e.g.
