1262202-24-3Relevant articles and documents
Chemical Synthesis of the Antiviral Nucleotide Analogue ddhCTP
Wood, James M.,Evans, Gary B.,Grove, Tyler L.,Almo, Steven C.,Cameron, Scott A.,Furneaux, Richard H.,Harris, Lawrence D.
, p. 8843 - 8850 (2021)
3′-Deoxy-3′,4′-didehydro-cytidine triphosphate (ddhCTP) is a novel antiviral molecule produced by the enzyme viperin as part of the innate immune response. ddhCTP has been shown to act as an obligate chain terminator of flavivirus and SARS-CoV-2 RNA-depen