1261524-75-7

Basic information

• Product Name: (3-BROMO-2-CHLOROPHENYL)METHANOL
• Synonyms: (3-BROMO-2-CHLOROPHENYL)METHANOL;3-Bromo-2-chlorobenzyl alcohol
• CAS NO: 1261524-75-7
• Molecular Formula: C₇H₆BrClO
• Molecular Weight: 221.47894
• EINECS: -0
• Mol File: 1261524-75-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 307.0±27.0 °C(Predicted)
• Appearance: /
• Density: 1.685±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.69±0.10(Predicted)
• CAS DataBase Reference: (3-BROMO-2-CHLOROPHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (3-BROMO-2-CHLOROPHENYL)METHANOL(1261524-75-7)
• EPA Substance Registry System: (3-BROMO-2-CHLOROPHENYL)METHANOL(1261524-75-7)

Safety Data

• Hazardous Substances Data: 1261524-75-7(Hazardous Substances Data)

Usage

General Description

(3-Bromo-2-chlorophenyl)methanol is a chemical compound with the molecular formula C7H6BrClO. It is a white crystalline solid that is used in various chemical and pharmaceutical applications. (3-BROMO-2-CHLOROPHENYL)METHANOL is a derivative of phenol and is commonly used as an intermediate in the production of pharmaceuticals and agrochemicals. It is also used as a building block for the synthesis of various organic molecules. (3-Bromo-2-chlorophenyl)methanol has several industrial and research applications due to its reactivity and versatility in organic synthesis. Additionally, it is important to handle this compound with caution as it can be hazardous if not used properly.

Upstream product

• 1197050-28-4 3-bromo-2-chloro-benzaldehyde 
• 56961-27-4 3-bromo-2-chloro-benzoic acid 
• 871224-19-0 methyl 3-bromo-2-chlorobenzoate 
• 120100-15-4 methyl 3-amino-2-chlorobenzoate 
• 53553-14-3 2-chloro-3-nitrobenzoic acid methyl ester 

Downstream Products

• 1374574-18-1 5-bromo-4-chloro-2-benzofuran-1(3H)-one 
• 1197050-28-4 3-bromo-2-chloro-benzaldehyde 
• 1044256-89-4 1-bromo-3-(bromomethyl)-2-chlorobenzene 
• 1400755-07-8 [2-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol 
• 1044256-91-8 (3-bromo-2-chlorophenyl)methanamine 

Relevant articles and documents

Novel biphenyl derivative as well as preparation method and medical application thereof

The invention relates to the field of medicinal chemistry, and discloses biphenyl derivatives with PD-1/PD-L1 inhibitory activity as well as a preparation method and application of the biphenyl derivatives. The invention further discloses a composition containing the biphenyl derivative with the PD-1/PD-L1 inhibitory activity or the pharmaceutically acceptable salt of the biphenyl derivative and a pharmaceutically acceptable carrier of the biphenyl derivative, and application of the biphenyl derivative in preparation of a PD-1/PD-L1 inhibitor. The compound can be used for treating tumors.

PYRIDAZINONES AND METHODS OF USE THEREOF

Disclosed are compounds according to Formula (A), and related tautomers and pharmaceutical compositions. Also disclosed are therapeutic methods, e.g., of treating kidney diseases, using the compounds of Formula (A).

PD-1/PD-L1 INHIBITORS

Compounds according to formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.