1242072-86-1

Basic information

• Product Name: 4-((2-methyl-5-phenylthiazol-4-yl)methyl)benzonitrile
• Synonyms: 4-((2-methyl-5-phenylthiazol-4-yl)methyl)benzonitrile
• CAS NO: 1242072-86-1
• Molecular Weight: 366.486
• Mol File: 1242072-86-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-((2-methyl-5-phenylthiazol-4-yl)methyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((2-methyl-5-phenylthiazol-4-yl)methyl)benzonitrile(1242072-86-1)
• EPA Substance Registry System: 4-((2-methyl-5-phenylthiazol-4-yl)methyl)benzonitrile(1242072-86-1)

Safety Data

• Hazardous Substances Data: 1242072-86-1(Hazardous Substances Data)

Upstream product

• 1192167-42-2 4-(1-hydroxy-1,3-diphenylprop-2-ynyl)benzonitrile 
• 62-55-5 thioacetamide 

Relevant articles and documents

Bronsted acid catalyzed cyclization of propargylic alcohols with thioamides. Facile synthesis of Di- and trisubstituted thiazoles

Figure presented. A general and efficient method to prepare 2,4-di- and trisubstituted thiazoles via p-TsOH·H2O-catalyzed cyclization of trisubstituted propargylic alcohols with thioamides is described. The reaction was accomplished in moderate to excellent product yields under mild conditions that did not require the exclusion of air and moisture and offers an operationally simplistic and convenient route to this synthetically useful aromatic heterocycle.