123837-56-9

Basic information

• Product Name: 2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester
• Synonyms: 2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester
• CAS NO: 123837-56-9
• Molecular Weight: 384.426
• Mol File: 123837-56-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester(123837-56-9)
• EPA Substance Registry System: 2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester(123837-56-9)

Safety Data

• Hazardous Substances Data: 123837-56-9(Hazardous Substances Data)

Upstream product

• 456-14-4 4-fluorobenzamidine hydrochloride 
• 459-57-4 4-fluorobenzaldehyde 
• 7152-15-0 ethyl 4-methyl-3-oxo-pentanoate 

Downstream Products

• 123930-31-4 5-{(E)-2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-vinyl}-2,4-bis-(4-fluoro-phenyl)-6-isopropyl-pyrimidine 
• 122253-83-2 5-{(Z)-2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-vinyl}-2,4-bis-(4-fluoro-phenyl)-6-isopropyl-pyrimidine 
• 122253-62-7 [2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-pyrimidin-5-ylmethyl]-triphenyl-phosphonium; bromide 
• 122254-02-8 (4R,6S)-6-{(E)-2-[2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-pyrimidin-5-yl]-vinyl}-4-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-pyran-2-ol 
• 122254-31-3 (4R,6S)-6-{(E)-2-[2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-pyrimidin-5-yl]-vinyl}-4-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-pyran-2-one 
• 122253-18-3 [2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-pyrimidin-5-yl]-methanol 
• 122253-41-2 5-Bromomethyl-2,4-bis-(4-fluoro-phenyl)-6-isopropyl-pyrimidine 
• 122252-95-3 2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-pyrimidine-5-carboxylic acid ethyl ester 

Relevant articles and documents

Synthesis and Biological Activity of New HMG-CoA Reductase Inhibitors. 1. Lactones of Pyridine- and Pyrimidine-Substituted 3,5-Dihydroxy-6-heptenoic (-heptanoic) Acids

Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids 2-4 have been synthesized.Extensive exploration of structure-activity relationships led to several compounds exceeding the inhibitory activity of mevinolin (1b)