122684-33-7Relevant articles and documents
[3+2] Cycloaddition-mediated synthesis of 3-methylsulfanyl-pyrrolidine-3-carboxylic acid methyl ester
Boga, Sobhana B.,Alhassan, Abdul-Basit,Cooper, Alan B.,Shih, Neng-Yang,Doll, Ronald J.
, p. 5315 - 5316 (2009)
1,3-Dipolar cycloaddition reactions are fundamental processes in organic chemistry. Herein we report [3+2] annulation of thiomethylacrylate 2 and azomethine ylide precursor 3 towards the synthesis of novel 3-methylsulfanyl-pyrrolidine 5. Alternatively, we
TRPML MODULATORS
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Paragraph 0317, (2021/06/26)
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
Protected Chloroethyl and Chloropropyl Amines as Conformationally Unrestricted Annulating Reagents
Shi, Qing,Meehan, Mariah C.,Galella, Michael,Park, Hyunsoo,Khandelwal, Purnima,Hynes, John,Dhar, T. G. Murali,Marcoux, David
supporting information, p. 337 - 340 (2018/01/28)
The purpose of this letter is to document the use of protected chloroethyl and chloropropyl amines as conformationally unrestricted ambiphilic reagents that undergo annulation reactions with Michael acceptors. This reaction is wide in scope and utilizes r